Infectious Complications of Percutaneous Vascular Closure Devices

Sohail, Muhammad R.; Khan, Akbar H.; Holmes, Jr., David R.; Wilson, Walter R.; Steckelberg, James M.; Baddour, Larry M.
August 2005
Mayo Clinic Proceedings;Aug2005, Vol. 80 Issue 8, p1011
Academic Journal
OBJECTIVE: To describe the infectious complications of percutaneous vascular closure devices (PVCDs) on the basis of our institutional experience with PVCDs and the published medical literature. PATIENTS AND METHODS: We retrospectively reviewed all cases of PVCD-related infection seen at the Mayo Clinic In Rochester, Minn, between January 1, 2000, and December 31, 2003, and searched the English language medical literature for all previously published reports. RESULTS: We identified 46 cases in the medical literature and 6 cases from our institutional database. The median age of patients was 63 years (range, 40-79 years). Diabetes mellitus and obesity were the most common comorbidities. The median incubation period from device Insertion to presentation with access-site infection was 8 days (range, 2-29 days). The most common presenting symptoms were pain, erythema, fever, swelling, and purulent drainage at the access site. Mycotic pseudoaneurysm (22 cases) was the most common complication. Staphylococcus aureus was responsible for most (75%) of the infections. All patients underwent surgical débridement, and 54% required reconstructive procedures. The median duration of antibiotic treatment was 28 days (range, 7-42 days). The mortality rate was 6% (3 patients). CONCLUSIONS: Infection associated with PVCD placement is uncommon but is an extremely serious complication. Morbidity is high, and aggressive medical and surgical interventions are required to achieve cure.


Related Articles

  • Reprint of Annotated Bibliographies and Library for Internists IV.  // Annals of Internal Medicine;Sep83, Vol. 99 Issue 3, p408 

    Announces the availability of a collective reprint which contains several annotated bibliographies compiled for the Medical Knowledge Self-Assessment Program. Approach in compiling the bibliographies; Other annotated bibliographies that are included in the reprint.

  • Book notes. Ehrlich, George E.; Cozzi, Phillip J. // Annals of Internal Medicine;08/17/99, Vol. 131 Issue 4, p315 

    Evaluates several books concerning medicine. `Rheumatology: Diagnosis and Therapeutics,' by J.J. Cush et al; `Blood and Bone: Poems by Physicians,' by A. Belli et al; `Medicine's 10 Greatest Discoveries,' by M. Friedman.

  • Books Received.  // Annals of Internal Medicine;4/1/89, Vol. 110 Issue 7, p580 

    Presents a list of books on medicine published as of April 1989.

  • Foreword. Easty, David // Current Medical Literature: Ophthalmology;2008, Vol. 18 Issue 2, preceding p41 

    A foreword to the May 2008 issue of "Current Medical Literature" is presented.

  • Foreword.  // Current Medical Literature: Ophthalmology;2009, Vol. 19 Issue 2, preceding p37 

    A foreword to "Current Medical Literature" is presented.

  • What's new in the new editions?  // BMJ: British Medical Journal (International Edition);10/13/90, Vol. 301 Issue 6756, p882 

    Lists several books related to medicine. 'Psychiatry for Students. Seventh edition,' by D. Stafford-Clark, P. Bridges, and D. Black; 'Clinical and Resuscitative Data: a Compendium of Intensive Medical and Anesthetic Resuscitative data. Fourth edition,' by R.P.H. Dunnill and M.P. Colvin; 'A...

  • Brandon/Hill selected list of print books and journals in allied health. Hills, Dorothy R.; Stickell, Henry N.; Levy, Gustave L.; Levy, Janet W. // Journal of the Medical Library Association;Jan2003, Vol. 91 Issue 1, p18 

    Recommends a list of print allied health publications. List of books on alternative and complementary therapy; List of books on anatomy and physiology; List of books on dental hygiene and dental assisting.

  • Books Received.  // JAMA: Journal of the American Medical Association;7/3/91, Vol. 266 Issue 1, p132 

    Offers information on several medical books. 'Inventing AIDS,' by Cindy Patton; 'Drug Abuse,' published by the Pan American Health Organization; 'Complex Mixtures and Cancer Risk,' edited by H. Vainio; 'Immunodiagnosis of Cancer,' edited by Ronald B. Herberman.

  • Foreword. Li, Christopher // Current Medical Literature: Breast Cancer;2007, Vol. 19 Issue 4, pIV 

    A foreword to the December 2007 issue of "Current Medical Literature" is presented.


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics