Tubular and interstitial renal disease due to immunologic mechanisms

Andres, Giuseppe A.; McCluskey, Robert T.
January 1975
Kidney International;Jan1975, Vol. 7 Issue 1, p271
Academic Journal
The article presents a study on the generation of tubular and interstitial lesions immunologic mechanisms. Tubular and interstitial lesions can result from immune complexes or from autoantibodies against tubular basement membrane constituents. The functional importance of these tubular deposits and the associated tubular and interstitial lesions remain to be evaluated. However, several patients have been found to have glucosuria with normal blood sugar concentrations. Researchers observed that the tubular deposits and associated tubular and interstitial changes may be partially responsible for renal functional impairment.


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