The Abortion Cocktail

Nathanson, Bernard N.
January 1996
First Things: A Monthly Journal of Religion & Public Life;Jan1996, Issue 59, p23
Presents an article focusing on drugs that post an impact on abortion. Description of folic acid antagonists and antimetabolites; Use of the methotrexate drug in abortion cocktail; Protection of human subjects in accordance with the Code of Federal Regulations in the U.S.


Related Articles

  • Sad confusion of look-alike tablets. Prakash, Bhanu // Indian Dermatology Online Journal;2010, Vol. 1 Issue 1, p50 

    The article looks into the hazards of similarly packaged medicinal tablets. A case report is presented about an accidental abortion due to an error in taking medication. The identical packaging of tablets methotrexate and folic acid is discussed. A list of suggestions is given to avoid errors in...

  • NATURAL STANDARD HERBAL/SUPPLEMENT SPOTLIGHT: FOLATE.  // Monthly Prescribing Reference;Jun2011, Vol. 27 Issue 6, pA.16 

    The article offers information on folate and its uses. The product has been divided into various grades as per its usage which includes folate deficiency, methotrexate toxicity and Alzheimer's disease. As stated, folate and folic acid are forms of a water-soluble B vitamin. Its side-effects and...

  • Genetic Variation May Predict Severity of Side Effects From Chemotherapy Drug; DNA Screening Could Customize Treatment.  // Ascribe Newswire: Medicine;6/25/2001, p1 

    Researchers from the Fred Hutchinson Cancer Research Center as well as the University of Washington schools of Medicine, Dentistry, and Public Health and Community Medicine have found out that nearly half of all Americans carry a genetic mutation that interferes with their ability to metabolize...

  • Increased transport of pteridines compensates for mutations in the high affinity folate transporter and contributes to methotrexate resistance in the protozoan parasite Leishmania tarentolae. K√ľndig, Christoph; Haimeur, Anass; Legare, Danielle; Papadopoulou, Barbara; Ouellette, Marc // EMBO Journal;5/1/99, Vol. 18 Issue 9, p2342 

    Functional cloning led to the isolation of a novel methotrexate (MTX) resistance gene in the protozoan parasite Leishmania. The gene corresponds to orfG, an open reading frame (ORF) of the LD1/CD1 genomic locus that is frequently amplified in several Leishmania stocks. A functional ORF G-green...

  • Human Reduced Folate Carrier Gene and Transcript Variants: Functional, Physiologic, and Pharmacologic Consequences. Matherly, Larry H. // Current Pharmacogenomics;Sep2004, Vol. 2 Issue 3, p287 

    The primary route for membrane transport of reduced folates into mammalian cells and tissues is the ubiquitously expressed reduced folate carrier (RFC). RFC is also involved in specialized tissue functions related to folates, including absorption across the intestinal epithelium and...

  • Refolinon.  // Royal Society of Medicine: Medicines;2002, p470 

    This article presents information on Refolinon, a proprietary, prescription-only preparation of calcium folinate. It can be used to counteract the folate-antagonist activity and consequent toxic effects of certain drugs, especially methotrexate. It is available as tablets and in a form for...

  • The effect of malignant effusions on methotrexate disposition. Li, Jing; Gwilt, Peter // Cancer Chemotherapy & Pharmacology;Nov2002, Vol. 50 Issue 5, p373 

    Purpose. The purpose of this study was to evaluate the effect of malignant effusions on the pharmacokinetics of methotrexate (MTX). Methods. Simulated drug concentrations in blood, tissues and effusion fluid spaces were generated using a previously published physiologically based pharmacokinetic...

  • Sustained release of methotrexate through liquid-crystalline folate nanoparticles. Misra, Rahul; Mohanty, Sanat // Journal of Materials Science: Materials in Medicine;Sep2014, Vol. 25 Issue 9, p2095 

    To make chemotherapy more effective, sustained release of the drug is desirable. By controlling the release rates, constant therapeutic levels can be achieved which can avoid re-administration of drug. This helps to combat tumors more effectively with minimal side effects. The present study...

  • Curcumin and folic acid abrogated methotrexate induced vascular endothelial dysfunction. Sankrityayan, Himanshu; Majumdar, Anuradha S. // Canadian Journal of Physiology & Pharmacology;2016, Vol. 94 Issue 1, p89 

    Methotrexate, an antifolate drug widely used in rheumatoid arthritis, psoriasis, and cancer, is known to cause vascular endothelial dysfunction by causing hyperhomocysteinemia, direct injury to endothelium or by increasing the oxidative stress (raising levels of 7,8-dihydrobiopterin). Curcumin...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics