TITLE

Risk of hypertension and reduced kidney function after acute gastroenteritis from bacteria-contaminated drinking water

AUTHOR(S)
Garg, Amit X.; Moist, Louise; Matsell, Douglas; Thiessen-Philbrook, Heather R.; Haynes, R. Brian; Suri, Rita S.; Salvadori, Marina; Ray, Joel; Clark, William F.
PUB. DATE
August 2005
SOURCE
CMAJ: Canadian Medical Association Journal;8/2/2005, Vol. 173 Issue 3, p261
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Background The long-term health consequences of acute bacterial gastroenteritis remain uncertain. We studied the risk of hypertension and reduced kidney function after an outbreak of acute gastroenteritis due to contamination of a regional drinking water supply with Escherichia coli O157:H7 and Campylobacter species. Methods A total of 1958 adults with no known history of hypertension or kidney disease before the outbreak participated in a long-term follow-up study. Of the participants, 675 had been asymptomatic during the outbreak, 909 had had moderate symptoms of acute self-limited gastroenteritis, and 374 had had severe symptoms that necessitated medical attention. The outcomes of interest were a diagnosis of hypertension or the presence of reduced kidney function and albuminuria during the follow-up period. Results After a mean follow-up of 3.7 years after the outbreak, hypertension was diagnosed in 27.0% of participants who had been asymptomatic during the outbreak and in 32.3% and 35.9% of those who had had moderate and severe symptoms of acute gastroenteritis respectively (trend p = 0.009). Compared with the asymptomatic participants, those with moderate and severe symptoms of gastroenteritis had an adjusted relative risk of hypertension of 1.15 (95% confidence interval [CI] 0.97-1.35) and 1.28 (95% CI 1.04-1.56) respectively. A similar graded association was seen for reduced kidney function, defined as the presence of an estimated glomerular filtration rate below 60 mL/min per 1.73 m2 (trend p = 0.03). No association was observed between gastroenteritis and the subsequent risk of albuminuria. Interpretation Acute bacterial gastroenteritis necessitating medical attention was associated with an increased risk of hypertension and reduced kidney function 4 years after infection. Maintaining safe drinking water remains essential to human health, as transient bacterial contaminations may have implications well beyond a period of acute self-limited illness.
ACCESSION #
17679331

 

Related Articles

  • A software monitor for intermittent bacteria contamination in urban rivers. Mietzel, T.; Frehmann, T.; Geiger, W.F.; Schilling, W. // Water Science & Technology;2003, Vol. 47 Issue 2, p165 

    Norwegian receiving waters are of such high water quality that authorities consider opening them for bathing. The leading parameter to monitor the quality of bathing waters is fecal coliform bacteria (FC). For this parameter no rapid detection method is available. The main objective of this case...

  • My water in the millennium. Siddiqui // Economic Review (05318955);Aug99, Vol. 30 Issue 8, p78 

    Focuses on the water supply of Karachi, Pakistan. Pollution of the Indus River; Contamination contributed by human feces and industrial wastes; Efforts to promote safe drinking water.

  • Drinking water contamination in Walkerton, Ontario: positive resolutions from a tragic event. R. Holme // Water Science & Technology;Feb2003, Vol. 47 Issue 3, p1 

    In May 2000, Escherichia coli 0157:H7 and Campylobacter jejuni contaminated the drinking water supply in Walkerton, Ontario. Seven people died and over 2,000 were ill as a result. The Ontario Provincial Government set up a judicial Inquiry into the circumstances surrounding the outbreak and also...

  • Why Is Xenobiotics part of our vocabulary? Hunsinger, Ronald B.; Ongerth, Jerry E. // Journal: American Water Works Association;Aug2004, Vol. 96 Issue 8, p93 

    Examines the emergence of a contaminant as a water quality issue. Issues concerning the detection of contaminants in the water industry; Inclusion of the contaminant Bacillus coli into the drinking water standards; Emergence of water quality contaminants despite technological advances; Factors...

  • The role of algae in causing coliform problems within the distribution system. Lake, R.; Driver, S. // Water Science & Technology: Water Supply;2002, Vol. 2 Issue 4, p105 

    Assesses the influence that the algal bloom has on the presence of coliforms. It has been shown that there is a strong link between the end of the algal bloom and coliforms being found in the distribution system. The algal bloom does not allow coliforms to pass through the treatment works....

  • First Molecular Detection of Group A Rotaviruses in Drinking Water Sources in Beijing, China. X. Q. He; L. Cheng; D. Y. Zhang; W. Li; X. M. Xie; Ma, M.; Z. J. Wang // Bulletin of Environmental Contamination & Toxicology;Jul2009, Vol. 83 Issue 1, p120 

    The most prevalent group A rotavirus found in the diarrheic children was also determined in drinking water sources including raw water, treated water and tap water in Beijing, and then the possible contamination contributions to tap water for human consumption were discussed in this study. A...

  • EPA Agrees To Move on Toxics in Water.  // National Wildlife (World Edition);Apr/May84, Vol. 22 Issue 3, p32 

    Reports on the possible risk of contamination of the water supply in the U.S. due to the chemicals entering the environment each year from industrial facilities, abandoned dumps, leaking landfills and other sources. U.S. Congress' passage of the Safe Drinking Water Act to provide a framework...

  • THE POLLUTION OF WATER RESOURCES IN THE ESKISEHIR REGION WITHIN THE PORSUK RIVER BASIN, TURKEY. Galip, Yuce; Arzu, Pinarbasi; Sakir, Ozcelik; Didem, Ugurluoglu // Environmental Engineering & Management Journal (EEMJ);2004, Vol. 3 Issue 3, p323 

    Study area is about 500 km² including Eskisehir city center. Recently, industry in the region has been developing accelerated rate. Quality problems in surface and groundwater in the Eskisehir plain are investigated regarding organic elements. Irrigation and usage water (after treatment...

  • Everything in the kitchen sink. Silverstein, Kenneth // American City & County;Mar1994, Vol. 109 Issue 3, p26 

    Reports on nonpoint pollution as a threat to the United States' drinking water supply. Infestation of Milwaukee, Wisconsin drinking water with Cryptosporidium; Statistics on impaired water sites polluted primarily by toxic point sources; Number of publicly-owned waste-water facilities...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics