An in vitro approach to the study of macula densa-mediated glomerular hemodynamics

Ito, Sadayoshi; Carretero, Oscar A.
December 1990
Kidney International;Dec1990, Vol. 38 Issue 6, p1206
Academic Journal
The article presents information on an in vitro preparation for the study of macula densa-mediated glomerular hemodynamics. Tubuloglomerular feedback (TGF) operates between the tubule and the parent glomerulus. It is important to renal autoregulation and homeostasis of body fluid and electrolytes. Since the juxtaglomerular apparatus displays an intimate anatomical relationship between the specialized tubular epithelial cells (macula densa) and the vasculature, it has long been suggested as the anatomical site of TGF.


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