TITLE

Tolerance of Nonsteroidal Antiinflammatory Drugs in Patients With Inflammatory Bowel Disease

AUTHOR(S)
Bonner, Gregory F.; Walczak, Michelle; Kitchen, Laurel; Bayona, Manuel
PUB. DATE
August 2000
SOURCE
American Journal of Gastroenterology;Aug2000, Vol. 95 Issue 8, p1946
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
OBJECTIVE: We sought to examine whether use of nonsteroidal antiinflammatory drugs (NSAIDs) in an outpatient inflammatory bowel disease (IBD) population is associated with an increased likelihood of active disease. METHODS: We reviewed records of initial outpatient visits of IBD patients to the principal author from June 1995 to December 1997, with regard to use of aspirin and other NSAIDs and disease activity. RESULTS: Of 40 Crohn's patients seen with active disease, three (7.5%) were using NSAIDs; 14 of 72 (19.4%) Crohn's patients seen with inactive disease were using NSAIDs. Fifty-eight ulcerative colitis patients were seen with active disease, with eight (13.7%) using NSAIDs. Among 21 UC patients initially seen while in remission, five (23.8%) were using NSAIDs. CONCLUSIONS: Among this group of outpatients, NSAID use was not associated with a higher likelihood of active IBD. NSAID use in IBD deserves further study before recommending that patients refrain from their use under all circumstances.
ACCESSION #
17651364

 

Related Articles

  • Effects of Nonsteroidal Antiinflammatory Drugs on Inflammatory Bowel Disease: A Case-Control Study. Felder, Joseph B.; Korelitz, Burton I.; Rajapakse, Ramona; Schwarz, Samuel; Horatagis, Angelo P.; Gleim, Gilbert // American Journal of Gastroenterology;Aug2000, Vol. 95 Issue 8, p1949 

    OBJECTIVE: The aim of this study was to determine whether a relationship exists between the use of nonsteroidal anti-inflammatory drugs (NSAIDs) and exacerbation or onset of inflammatory bowel disease (IBD). METHODS: Sixty consecutive IBD patients admitted to the hospital were carefully...

  • Use of Cyclo-Oxygenase Inhibitors Is Not Associated with Clinical Relapse in Inflammatory Bowel Disease: A Case-Control Study. Hensley, Abigail; Beales, Ian L. P. // Pharmaceuticals;Sep2015, Vol. 8 Issue 3, p512 

    Patients with inflammatory bowel disease (IBD) often have associated conditions, for which anti-inflammatory medication with cyclo-oxygenase (COX) inhibitors may be helpful. The current evidence is conflicting regarding the role of COX-inhibitors in causing relapse in IBD. This case-control...

  • Targeting leukocyte migration and adhesion in Crohn's disease and ulcerative colitis. Thomas, Saskia; Baumgart, Daniel // Inflammopharmacology;Feb2012, Vol. 20 Issue 1, p1 

    Crohn's disease and ulcerative colitis are two chronic inflammatory bowel diseases. Current biologic therapies are limited to blocking tumor necrosis factor alpha. However, some patients are primary non-responders, experience a loss of response, intolerance or side effects defining the urgent...

  • The Month of Birth is Linked to the Risk of Crohn's Disease in the Israeli Population. Chowers, Yehuda; Odes, Shmuel; Bujanover, Yoram; Eliakim, Rami; Bar Meir, Simon; Avidan, Benjamin // American Journal of Gastroenterology;Oct2004, Vol. 99 Issue 10, p1974 

    OBJECTIVE: The main objective is to study whether the month of birth is associated with the development of Crohn's disease (CD) in the Israeli Jewish population.BACKGROUND: It was suggested that perinatal exposure to infectious agents may have a role in the pathogenesis of CD. Due to the...

  • Inflammatory bowel disease.  // Good Health (Australia Edition);Jan2013, p127 

    The article presents information on inflammatory bowel disease (IBD) , its causes and what can be done to avoid it. IBD is used for describing two chronic disorders including ulcerative colitis and Crohn's disease. However, the causes of ulcerative colitis and Crohn's disease are not known. It...

  • CARD15 Genotype-Phenotype Relationships in a Small Inflammatory Bowel Disease Population with Severe Disease Affection Status. Nigel Crawford; Daniel Colliver; M. Eichenberger; Alisa Funke; Valentina Kolodko; Gary Cobbs; Robert Petras // Digestive Diseases & Sciences;Oct2007, Vol. 52 Issue 10, p2716 

    Abstract  Inflammatory bowel disease (IBD; MIM# 266600) is subdivided on the basis of clinical findings as either Crohn’s disease (CD), ulcerative colitis (UC), or indeterminate colitis (IC). Three previously described mutations within the IBD susceptibility gene...

  • Serum antibodies associated with complex inflammatory bowel disease. Balzola, Federico; Cullen, Garret; Ho, Gwo-Tzer; Russell, Richard K. // Inflammatory Bowel Disease Monitor;2013, Vol. 14 Issue 1, p19 

    The article presents a study that examines the serological profile of patients with inflammatory bowel disease such as Crohn's disease and ulcerative colitis (UC). It offers details of the method of the study that uses a multivariate analysis to determine the relationship of serologies to young...

  • The prevalence and outcome of jejunal lesions visualized by small bowel endoscopy in Crohn's disease. Balzola, Federico; Cullen, Garret; Ho, Gwo-Tzer; Russell, Richard K. // Inflammatory Bowel Disease Monitor;2013, Vol. 14 Issue 1, p26 

    The article presents a study that determines the prevalence and outcome of jejunal lesions in patients with Crohn's disease. It describes the method of the study that uses small bowel capsule endoscopy for accurate visualization of lesions on the mucosal surface. It notes the result of the study...

  • Mortality and causes of death in Crohn's disease: results from 20 years of follow-up in the IBSEN study. Balzola, Federico; Cullen, Garret; Ho, Gwo-Tzer; Russell, Richard K. // Inflammatory Bowel Disease Monitor;2013, Vol. 14 Issue 1, p27 

    The article presents a study that determines the mortality and causes of death in patients with Crohn's disease. It describes the method of the Inflammatory Bowel South-Eastern Norway (IBSEN) to investigate the mortality of the disease after 20 years. It notes the result of the study which...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics