Progressive Gastrointestinal Histoplasmosis Leading to Colonic Obstruction Two Years After Initial Presentation

Hertan, Hilary; Nair, Satheesh; Arguello, Pedro
January 2001
American Journal of Gastroenterology;Jan2001, Vol. 96 Issue 1, p221
Academic Journal
A 37-yr-old man from Ecuador presented with abdominal pain, diarrhea, and weight loss. Endoscopy revealed duodenal histoplasmosis. The patient improved with antifungal therapy but was readmitted 2 yr later with diarrhea and fever. Colonoscopy revealed histoplasmosis lesions, including a constricting transverse colon lesion. The patient refused surgery and died of colonic perforation. We discuss the diagnosis and management of gastrointestinal histoplasmosis in this report.


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