Effect of Age on Differences in Upper Esophageal Sphincter and Pharynx Pressures Between Patients With Dysphagia and Control Subjects

Meier-Ewert, H. K.; M. A., Van Herwaarden; Gideon, R. M.; Castell, J. A.; Achem, S.; Castell, D. O.
January 2001
American Journal of Gastroenterology;Jan2001, Vol. 96 Issue 1, p35
Academic Journal
OBJECTIVES: The aim of this study was to explore the effect of age and food consistency on manometric data of the swallow sequence in patients with dysphagia. METHODS: Manometric data from 41 patients (age range. 32-88 yr) and 41 age-matched control subjects was examined for differences between subgroups <60 yr and ≥60 yr of age, as well as for changes with food consistency. RESULTS: Only pharynx peak pressure showed an age-dependent decrease (144.1 ± 21.4 mm Hg vs 95.8 ± 15.1 mm Hg. p < 0.05) in patients. Significant higher upper esophageal sphincter residual pressure and delayed onset of upper esophageal sphincter relaxation were noted in patients aged <60 yr compared to age-matched controls, whereas only pharynx peak pressure was significantly lower in patients compared to controls aged ≥60 yr. Food consistency did not have a consistent effect on manometric results in patients with dysphagia. CONCLUSIONS: This is the first study to systematically explore the influence of age and food consistency on manometric parameters in dysphagia patients. These results may provide useful insights when identifying actual manometric abnormalities in patients with dysphagia. They also suggest possible different underlying mechanism of dysphagia in younger versus older patients.


Related Articles

  • An unusual case of dysphagia. Agarwal, Lekha; Eu Chin Ho; Glossop, Lawrence P. // ENT: Ear, Nose & Throat Journal;Dec2006, Vol. 85 Issue 12, p813 

    The article focuses on a 90-year-old man with a 2-year history of progressive dysphagia. A smooth midline swelling in the posterior pharyngeal wall has been detected through flexible nasendoscopy. It was found that a large anterior cervical osteophyte was present from C3 down to C7 and had...

  • Balloon Sensors for the Manometric Recording of the Pharyngoesophageal Tract: An Experimental Study. Mattioli, Sandro; Lugaresi, Marialuisa; Zannoli, Romano; Brusori, Stefano; d’Ovidio, Franco // Dysphagia (0179051X);Oct2003, Vol. 18 Issue 4, p249 

    The goal of our study was to investigate manometric balloon sensors of original conception in order to overcome the limitations of perfused and solid-state sensors in the assessment of the pharyngoesophageal motility abnormalities. A standard perfused probe for esophageal manometry was modified...

  • Referral, diagnosis and management of dysphagia.  // Pulse;2/28/2005, Vol. 65 Issue 8, p64 

    The article focuses on referral, diagnosis and management of dysphagia. Swallowing is a physiological function essential to the maintenance of life and one people take for granted, yet dysphagia is a common complaint in general practice. Food and drink are conveyed to the mouth through sucking...

  • Oropharyngeal Dysphagia in Paget's Disease of Bone (Osteitis Deformans): Response to Calcitonin. Frank, Michael S.; Brandt, Lawrence J.; Kaufman, David M.; Barzel, Uriel; Lynch, John; Goldberg, Lawrence; Bernstein, Leslie H. // American Journal of Gastroenterology;Jul1982, Vol. 77 Issue 7, p450 

    Presents a case report of a patient with Paget's disease and progressive oropharyngeal dysphagia that was most likely secondary to a bulbar palsy. Medical history; Result of the physical examination; Definition of oropharyngeal dysphagia; Cause of bulbar palsy and secondary oropharyngeal dysphagia.

  • Rehabilitation medicine: 2. Diagnosis of dysphagia and its nutritional management for stroke patients. Finestone, Hillel M.; Greene-Finestone, Linda S. // CMAJ: Canadian Medical Association Journal;11/11/2003, Vol. 169 Issue 10, p1041 

    FOLLOWING STROKE, PATIENTS MAY HAVE REDUCED DIETARY intake, swallowing impairments (dysphagia) and other neurological deficits that could affect their nutritional and hydration status and lead to aspiration pneumonia. Impaired nutritional status is associated with reduced functional improvement,...

  • Use of a cutting balloon in the dilatation of caustic oesophageal stricture. Wilkinson, A. Graham; MacKinlay, Gordon A. // Pediatric Radiology;May2004, Vol. 34 Issue 5, p414 

    A 14-year-old boy was admitted with absolute dysphagia 1 year after he had swallowed drain cleaner. Contrast swallow showed a tight stricture of the whole of the oesophagus below the level of T2. Attempted dilatation to 8 mm using conventional balloons was performed on two occasions, but there...

  • Small Cell Carcinoma of the Esophagus in a Patient with Longstanding Primary Achalasia. Proctor, Deborah D.; Fraser, Jean L.; Mangano, Mark M.; Calkins, David R.; Rosenberg, Stanley J. // American Journal of Gastroenterology;May1992, Vol. 87 Issue 5, p664 

    Achalasia is believed to be a predisposing factor for the development of esophageal cancer. Small cell carcinoma of the esophagus is a rare neoplasm, with fewer than 150 cases having been reported in the world literature, and it has been described only once previously in a patient with...

  • Actinomyces Infection of a Cytomegalovirus Esophageal Ulcer in Two Patients with Acquired Immunodeficiency Syndrome. Poles, Michael A.; McMeeking, Alexander A.; Scholes, John V.; Dieterich, Douglas T. // American Journal of Gastroenterology;Sep1994, Vol. 89 Issue 9, p1569 

    Esophageal disease is a significant cause of morbidity among patients with the acquired immunodeficiency syndrome (AIDS). Many organisms have been implicated in the pathogenesis of dysphagia and odynophagia. We describe a unique presentation of actinomyces esophageal infection in two homosexual...

  • Cricopharyngeal Myotomy Does Not Increase the Risk of Esophagopharyngeal Acid Regurgitation. Williams, Rohan B. H.; Ali, Galib N.; Hunt, David R.; Wallace, Karen L.; Cook, Ian J. // American Journal of Gastroenterology;Dec1999, Vol. 94 Issue 12, p3448 

    OBJECTIVE: It is not known whether cricopharyngeal myotomy predisposes to esophagopharyngeal regurgitation. Using ambulatory, dual pharyngeal, and esophageal pH monitoring before and after cricopharyngeal myotomy, our aim was to determine the effect, if any, of myotomy on the frequency of...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics