Fatal Heart Block Following Treatment With Botulinum Toxin for Achalasia

Malnick, Stephen D. H.; Metchnik, Laura; Somin, Marina; Bergman, Nina; Attali, Malka
November 2000
American Journal of Gastroenterology;Nov2000, Vol. 95 Issue 11, p3333
Academic Journal
Reports on the case of a patient with achalasia who developed a fatal heart block after receiving an injection of botulinum toxin. Medical history of the patient; Result of the patient's esophagogastroduodenoscopy; Mechanism of action of botulinum toxin.


Related Articles

  • Treatment of achalasia: the short-term response to botulinum toxin injection seems to be independent of any kind of pretreatment. Storr, M.; Born, P.; Frimberger, E.; Weigert, N.; Rösch, T.; Meining, A.; Classen, M.; Allescher, H. D. // BMC Gastroenterology;2002, Vol. 2, p19 

    Background: It has been suggested that intrasphincteric injection of botulinum toxin (BTX) may represent an alternative therapy to balloon dilatation in achalasia. The aim of the present study was to test the effectiveness of botulinum toxin injections in achalasia patients, as assessed using...

  • Prospective Study of Esophageal Botulinum Toxin Injection in High-Risk Achalasia Patients. Gordon, James M.; Eaker, Ervin Y. // American Journal of Gastroenterology;Oct1997, Vol. 92 Issue 10, p1812 

    Objectives: Intrasphincteric injection of botulinum toxin has been reported as a safer treatment alternative to balloon dilation or myotomy in achalasia. We studied botulinum toxin injection in achalasia patients who are at high surgical risk because of age or concomitant medical problems....

  • Achalasia of the Esophagus. Liebman, William M.; Applebaum, Michael; Thaler, M. Michael // American Journal of Gastroenterology;Jul1978, Vol. 70 Issue 1, p73 

    A four-year old boy with achalasia of the esophagus was successfully treated with pneumatic dilatation, using the standard Browne-McHardy dilator, without incident. His subsequent course over 10 months has been uneventful.

  • Botulinum toxin A.  // Reactions Weekly;10/8/2011, Issue 1372, p11 

    The article cites a case of an elderly patient who developed botulism-like syndrome after receiving botulinum toxin A for esophageal achalasia.

  • The Value of Scoring Achalasia: A Comparison of Current Systems and the Impact on Treatment--The Surgeon's Viewpoint. Gockel, I.; Junginger, Th. // American Surgeon;Apr2007, Vol. 73 Issue 4, p327 

    Heller myotomy in patients with achalasia promises better long-term success than pneumatic dilation, especially in younger patients, and therefore has evolved as the primary treatment option. The aim of this study was to evaluate the impact of different disease-specific severity scores on...

  • “Corkscrew” Esophagus. Dheer, Sachin; Chang, Raymond // New England Journal of Medicine;4/24/2003, Vol. 348 Issue 17, p1671 

    The article discusses the case study of an 89-year-old woman sufferring with corkscrew esophagus. She was referred for an upper gastrointestinal examination due to dysphagia, epigastric pain, and frequent belching. A single-contrast barium examination of esophagus of the patient showed a...

  • Age Affects Presenting Symptoms of Achalasia and Outcomes after Myotomy. Rakita, Steven; Bloomston, Mark; Villadolid, Desiree; Thometz, Donald; Boe, Brian; Rosemurgy, Alexander // American Surgeon;May2005, Vol. 71 Issue 5, p424 

    Older patients with achalasia presumably have had a longer, more indolent course than younger patients. This study was undertaken to determine the impact of patient age and duration of symptoms on symptom severity and outcome after Heller myotomy. Two hundred sixty-two patients (142 men and 120...

  • A small dose of poison helps the nutriments go down.  // Patient Care;11/15/1995, Vol. 29 Issue 18, p9 

    Presents the result of the study on the treatment of achalasia by botulinum toxin in a randomized, double-blind, placebo-controlled study. Benefits of botulin toxin to several patients; Alternative medicine for the treatment of achalasia.

  • Excellent outcomes of laparoscopic esophagomyotomy for achalasia in patients older than 60 years of age. Roll, Garrett R.; Ma, Sandi; Gasper, Warren J.; Patti, Marco; Way, Lawrence W.; Carter, Jonathan // Surgical Endoscopy;Oct2010, Vol. 24 Issue 10, p2562 

    Background: The effectiveness of an esophagomyotomy for dysphagia in elderly patients with achalasia has been questioned. This study was designed to provide an answer. Methods: A total of 162 consecutive patients with achalasia who had a laparoscopic myotomy and Dor fundoplication and who were...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics