TITLE

Lifestyle Habits and Gastric Cancer in a Hospital-Based Case-Control Study in Taiwan

AUTHOR(S)
Mei-Ju Chen; Yuan-Yow Chiou; Deng-Chyang Wu; Shu-Ling Wu
PUB. DATE
November 2000
SOURCE
American Journal of Gastroenterology;Nov2000, Vol. 95 Issue 11, p3242
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
OBJECTIVES: The aim of this study was to evaluate the effect of lifestyle habits on the risk of primary gastric cancer. METHODS: A hospital-based case-control study of matched pairs was conducted in Kaohsiung, Taiwan, from 1992 to 1996. The study included 649 subjects (152 cases and 497 controls). All subjects were personally interviewed face-to-face by a trained interviewer using a structured questionnaire to collect data about lifestyle. An average of approximately three controls were matched to each case based on age (±3 yr), sex, and time of hospitalization (±2 wk). Adjusted odds ratios (ORs) and 95% confidence intervals (95% CIs) were used to evaluate results, and a multivariate analysis of the data was performed using a conditional logistic regression model. RESULTS: A significantly elevated risk of contracting gastric cancer was observed in cigarette smokers (OR: 2.7, 95% CI: 1.5-4.3), hut not in drinkers of alcoholic beverages (OR: 1.5, 95% CI: 0.9-3.2). A synergistically augmented relationship (multiplication effect) was found between smoking and drinking alcohol for controlling the major confounders. The combined adjusted ORs for all subjects with gastric cancer were 3.0 (95% CI: 1.4-7.1) for current smokers and 1.7 (95% CI: 1.2-4.4) for ex-smokers. Furthermore, a statistically significant positive dose-response trend in gastric cancer was demonstrated based on the age at which smoking was initiated, the duration of the habit, the number of cigarettes smoked per day, and the degree of smoke inhalation. We did not find any association between the other risk factors and gastric carcinogenesis. CONCLUSIONS: Our findings provide further evidence that in Taiwan, cigarette smoking may play the most harmful role in the initial development of gastric cancer, and that drinking alcohol may promote the process.
ACCESSION #
17628626

 

Related Articles

  • The Natural History of Ulcerative Proctitis: A Multicenter, Retrospective Study. Meucci, Gianmichele; Vecchi, Maurizio; Astegiano, Marco; Beretta, Luigi; Cesari, Pietro; Dizioli, Paolo; Ferraris, Luca; Panelli, Maria Rita; Prada, Alberto; Sostegni, Raffaello; de Franchis, Roberto // American Journal of Gastroenterology;Feb2000, Vol. 95 Issue 2, p469 

    OBJECTIVE: The aim of this study was to evaluate the clinical features and the long term evolution of patients with a well defined initial diagnosis of ulcerative proctitis. METHODS: Patients with an original diagnosis of ulcerative proctitis who had been seen at any of 13 institutions from 1989...

  • A not so uncommon cause of abdominal pain. Spiller, Robin // Gut;Jul2008, Vol. 57 Issue 7, p877 

    A quiz concerning the diagnosis of a 53-year-old male hypertensive smoker with a 1-day history of sudden onset left iliac fossa pain with nausea is presented.

  • The role of tobacco promoting and restraining factors in smoking intentions among Ghanaian youth. Doku, David; Raisamo, Susanna; Wiium, Nora // BMC Public Health;2012, Vol. 12 Issue 1, p662 

    Background: In Western countries, the relationship between smoking intentions and smoking behaviour is well established. However, youth smoking intentions and associated factors in developing countries are largely unexplored and the former may occur for a variety of reasons. We investigated...

  • Factors associated with adolescent cigarette smoking in Greece: results from a cross sectional study (GYTS Study). Petticrew, Mark; Platt, Stephen; McCollam, Allyson; Wilson, Sarah; Thomas, Sian // BMC Public Health;2008, Vol. 8 Issue 1, p313 

    Background: Data about the predictors of smoking among adolescents in Greece are sparse. We tried to identify factors associated with current cigarette smoking among in-school adolescents in Greece in the context of GYTS study. Methods: A secondary analysis of data from a questionnaire study...

  • Impact of smoking on asthma symptoms, healthcare resource use, and quality of life outcomes in adults with persistent asthma. Shavit, Oren; Swern, Arlene; Qian Dong; Newcomb, Kathleen; Sazonov Kocevar, Vasilisa; Taylor, Stephanie D.; Dong, Qian // Quality of Life Research;Dec2007, Vol. 16 Issue 10, p1555 

    Background: Smoking habits of asthmatics are similar to those of the general population. However, little attention has been paid to the associations between smoking and asthma-related outcomes.Objective: To evaluate relationships between cigarette smoking, asthma...

  • Predicting participation and outcome in four workplace smoking intervention programmes. Hallett, Robert; Sutton, Stephen R. // Health Education Research;Sep1987, Vol. 2 Issue 3, p257 

    The article focuses on four workplace smoking intervention programmes. An analysis predicting expression of interest in taking part in a programme, attendance and outcome among cigarette smokers has been conducted. The four companies involved in the study had employee rolls ranging from 587 to...

  • Smoking Behavior in a Teenage Population: A Multivariate Conceptual Approach. Lanese, Richard R.; Banks, Franklin R.; Keller, Martin D. // American Journal of Public Health;Jun1972, Vol. 62 Issue 6, p807 

    In studies of variables that can be used to predict teenage smoking, there is a need for surveys using multiple prediction procedures. This paper is an attempt to select an optimum set of such predictors and to establish their interrelationships. Findings are presented and areas of research are...

  • Predictors of Different Cigarette Access Behaviours Among Occasional and Regular Smoking Youth. Leatherdale, Scott T. // Canadian Journal of Public Health;Sep/Oct2005, Vol. 96 Issue 5, p348 

    Background: Understanding the different ways underage youth access tobacco is required in order to develop more effective tobacco access restrictions. The purpose of this study was to examine characteristics that predict whether underage smoking youth buy their own cigarettes, buy their...

  • Smoking status at diagnosis and histology type as determinants of long-term outcomes of lung cancer patients. Poullis, Michael; McShane, James; Shaw, Mathew; Shackcloth, Michael; Page, Richard; Mediratta, Neeraj; Gosney, John // European Journal of Cardio-Thoracic Surgery;May2013, Vol. 43 Issue 5, p919 

    OBJECTIVES The study aimed to determine the importance of smoking status at operation and histology type with regard to long-term survival after potential curative surgery for lung cancer. METHODS We analysed a prospectively validated thoracic surgery database (n = 2485). We benchmarked our...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics