TITLE

Cholesterol Crystal Embolization Demonstrated on GI Biopsy

AUTHOR(S)
Paraf, François; Jacquot, Christian; Bloch, Francis; De Montpréville, Vincent; Bruneval, Patrick
PUB. DATE
December 2001
SOURCE
American Journal of Gastroenterology;Dec2001, Vol. 96 Issue 12, p3301
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
OBJECTIVES: Cholesterol crystal embolism is a severe complication of atherosclerosis responsible for nonspecific cutaneous, renal, and, less often, digestive manifestations that may mimic other systemic diseases. METHODS: We reviewed retrospectively 10 patients with histologically proven cholesterol crystal emboli diagnosed by endoscopic GI biopsy. RESULTS: All patients had prior clinical manifestations of severe atherosclerosis and predisposing factors for cholesterol migration. They all had cutaneous manifestations of cholesterol crystal embolism, acute renal failure, and biological inflammatory syndrome. Digestive symptoms were found in the 10 patients: abdominal pain in eight, diarrhea in four, and GI bleeding in three. GI endoscopy ruled out specific digestive diseases, showing only a congestive or erosive mucosa. Histological diagnosis of cholesterol crystal emboli was based on gastric biopsy in nine patients, duodenal biopsy in four, colonic biopsy in three, and rectal biopsy in one, with six having positive biopsies on multiple sites. Outcome after the diagnosis of cholesterol crystal embolism was poor, with all patients requiring permanent hemodlalysis. Death by atherosclerosis complications occurred in five patients. CONCLUSIONS: This cohort suggests that upper GI endoscopy may be helpful in demonstrating the presence of cholesterol crystal embolism, and that diagnosis of cholesterol crystal emboli on digestive tract biopsy indicates advanced systemic atherosclerosis disease of poor prognosis.
ACCESSION #
17611829

 

Related Articles

  • Estrongiloidiosis. A propósito de un caso clínico. Álvarez, Salomé A.; Salazar, Janeth A.; Salazar, Elba A.; Vivar, Nicolás D. // Revista Mexicana de Patologia Clinica;oct-dic2010, Vol. 57 Issue 4, p209 

    No abstract available.

  • Unusual Differential Diagnosis of Upper Abdominal Pain. Monika, Lanthaler; Thomas, Grissmann; Lukas, Schwentner; Hermann, Nehoda // Diagnostic & Therapeutic Endoscopy;2009, p1 

    We here present an interesting unusual case of upper abdominal pain. The patient was a 38-year-old man, who was admitted to our hospital complaining of right upper quadrant pain caused by a toothpick that perforated the anterior gastric wall and penetrated segment I of the liver. After...

  • Gastric Electrical Stimulation for Abdominal Pain in Patients with Symptoms of Gastroparesis. LAHR, CHRISTOPHER J.; GRIFFITH, JAMES; SUBRAMONY, CHARU; HALLEY, LINDSEY; ADAMS, KRISTEN; PAINE, ELIZABETH R.; SCHMIEG, ROBERT; ISLAM, SALEEM; SALAMEH, JAY; SPREE, DANIELLE; KOTHARI, TRUPTESH; KEDAR, ARCHANA; NIKITINA, YANA; ABELL, THOMAS // American Surgeon;May2013, Vol. 79 Issue 5, p457 

    Abdominal pain physiology may be better understood studying electrophysiology, histology, and symptom scores in patients with the symptoms of gastroparesis (Gp) treated with gastric electrical stimulation (GES). Ninety-five Gp patients" symptoms were recorded at baseline and during temporary and...

  • 34-Year-Old Woman With Abdominal Pain and Blood-Streaked Diarrhea. Larsen, Carolyn M.; Nakamura, Kelly M.; Bhagra, Anjali // Mayo Clinic Proceedings;Sep2012, Vol. 87 Issue 9, p905 

    A medical quiz about a 34-year-old woman with abdominal pain and blood-streaked diarrhea is presented.

  • Dicrocoeliiasis with Signs of Chronic Diarrhea. Mahmoodi, Mohsen; Ramazani, Ali Reza Zahraei; Izadi, Shahrokh; Najafian, Jamshid // Acta Medica Iranica;2010, Vol. 48 Issue 3, p198 

    A case who was suffering from abdominal pain and chronic diarrhea refered to Isfahan Health Training and Research Center, Institute of Public Health. Current treatments for chronic diarrhea incloding a traial of gluten fre diet were performed but these were not effective because he was infected...

  • Cramping and Diarrhea in a 44-Year-Old Man. Lewis, Joseph Michael; Winslow, Helen; Jones, Jayne; Taegtmeyer, Miriam; O'Dempsey, Tim; Nsutebu, Emmanuel // Clinical Infectious Diseases;8/1/2015, Vol. 61 Issue 3, p432 

    The article presents case study of a 44-year-old man with upper abdominal pain associated with watery diarrhea up to 20 times each day and he was having medical history of intermittent sinusitis and asks about diagnosis of the clinical condition.

  • Clindamycin.  // Reactions Weekly;10/29/2016, Vol. 1625 Issue 1, p67 

    The article presents a case study of a patient who experienced bloody diarrhoea and abdominal pain after being medicated with clindamycin.

  • Multiple magnet ingestion and gastrointestinal morbidity. Cauchi, J.A.; Shawis, R.N. // Archives of Disease in Childhood;Dec2002, Vol. 87 Issue 6, p539 

    Presents the case of a 9-year-old girl presented with a four-day history of left sided abdominal pain with vomiting and diarrhea. Diagnosis of multiple magnet ingestion and gastrointestinal morbidity; Treatment procedure; Implications on acute pediatrics.

  • Transcatheter coil embolization of an iatrogenic superior mesenteric arteriovenous fistula: Report of a case. SHINTANI, TSUNEHIRO; MITSUOKA, HIROSHI; MASUDA, MIKIO // Surgery Today;Apr2011, Vol. 41 Issue 4, p556 

    37-year-old male patient presented with abdominal pain and diarrhea. Computed tomography showed a large superior mesenteric vein aneurysm. The patient had a history of Crohn's disease and underwent an ileocecal resection 7 years previously. A selective angiogram of the superior mesenteric artery...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics