TITLE

Silica: déjà vu all over again?

AUTHOR(S)
Steenland, K.
PUB. DATE
July 2005
SOURCE
Occupational & Environmental Medicine;Jul2005, Vol. 62 Issue 7, p430
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
In this article, the author comments on the paper regarding industrial hygiene by the researchers, Brown T. and Rushton T. Researchers had conducted a retrospective cohort mortality study of 2700 workers in the industrial sand industry. Work in the industrial sand industry results in exposure to crystalline silica, and the focus of the study was whether exposure to silica causes lung cancer. Retrospective exposure assessment, based on air measurements since 1978, and some measurements since 1978, and some assumptions about exposure before then, was used to estimate exposure levels for different jobs in the industry over time. Brown and Rushton did not find an excess of lung cancer in this cohort compared to the general population, nor did they find any excess silicosis. The author argues that the negative results of Brown and Rushton are not that surprising, for two reasons. First, IARC noted in 1997 that positive finding for lung cancers were not consistent across studies, and that specific mineralogic properties of the silica might vary and result in different levels of toxicity. Therefore it is quite possible that a given study might be negative. Second, the exposure levels in the Brown and Rushton study were rather low.
ACCESSION #
17563734

 

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