TITLE

LUNG ALERT........: Sildenafil and exercise capacity in hypoxic pulmonary hypertension

AUTHOR(S)
Mughal, M. M.
PUB. DATE
November 2004
SOURCE
Thorax;Nov2004, Vol. 59 Issue 11, p999
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article presents information about a study, which examined the influence of oral sildenafil on pulmonary haemodynamics, and exercise tolerance during hypoxia induced pulmonary hypertension in healthy mountaineers and trekkers who were not susceptible to high altitude pulmonary edema. The results of the study revealed that Sildenafil reduced hypoxic pulmonary hypertension at rest and with exercise, and increased maximum exercise capacity and cardiac output. The study did not examine the effects of sildenafil on normoxic exercise tolerance.
ACCESSION #
17563398

 

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