LUNG ALERT........: Sildenafil and exercise capacity in hypoxic pulmonary hypertension

Mughal, M. M.
November 2004
Thorax;Nov2004, Vol. 59 Issue 11, p999
Academic Journal
The article presents information about a study, which examined the influence of oral sildenafil on pulmonary haemodynamics, and exercise tolerance during hypoxia induced pulmonary hypertension in healthy mountaineers and trekkers who were not susceptible to high altitude pulmonary edema. The results of the study revealed that Sildenafil reduced hypoxic pulmonary hypertension at rest and with exercise, and increased maximum exercise capacity and cardiac output. The study did not examine the effects of sildenafil on normoxic exercise tolerance.


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