α1-Antitrypsin deficiency ∙ 7: Computed tomographic imaging in α1-antitrypsin deficiency

Shaker, S. B.; Stavngaard, T.; Stolk, J.; Stoel, B.; Dirksen, A.
November 2004
Thorax;Nov2004, Vol. 59 Issue 11, p986
Academic Journal
The article focuses on computed tomographic (CT) imaging in α1-antitrypsin deficiency. α1-antitrypsin (AAT) deficiency is characterized by a reduced serum AAT level down to about 20% of the normal level leading to the development of emphysema. CT scanning is the most sensitive method of diagnosing emphysema, determining its subtype and assessing its severity in vivo and both visual and quantitative CT scanning is closely correlated with the pathological extent of emphysema.


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