TITLE

A randomised, double-blind trial of topical ketorolac vs artificial tears for the treatment of episcleritis

AUTHOR(S)
Williams, C. P. R.; Browning, A. C.; Sleep, T. J.; Webber, S. K.; McGill, J. I.
PUB. DATE
July 2005
SOURCE
Eye;Jul2005, Vol. 19 Issue 7, p739
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
PurposeTo determine whether topical ketorolac (Acular) is more effective than artificial tears in treating the signs and symptoms of idiopathic episcleritis.MethodsIn this prospective, randomised, double-blind study, 38 eyes of 37 patients presenting with idiopathic episcleritis were allocated to receive either topical ketorolac (0.5%) or artificial tears three times a day for 3 weeks. The severity of patients’ signs (episcleral injection and the number of clock hours affected) were recorded at weekly intervals. Patients' symptoms (perceived redness and pain scores) were recorded using a daily diary.ResultsThere was no significant difference in the ophthalmic signs between the two groups at each assessment, including intensity of episcleral injection and the number of clock hours affected. No significant difference was found in the time to halve the baseline redness intensity scores (4.4 vs 6.1 days, P=0.2) or pain scores (3.6 vs 4.3 days, P=0.55). Significantly more patients on ketorolac reported stinging at the first follow-up visit (P<0.001).ConclusionTopical ketorolac is not significantly better than artificial tears in treating the signs or symptoms of idiopathic episcleritis.Eye (2005) 19, 739–742. doi:10.1038/sj.eye.6701632 Published online 10 September 2004
ACCESSION #
17550450

 

Related Articles

  • Upregulation of Matrix Metalloproteinase in Tear Fluid of Patients with Recurrent Corneal Erosion. Tohru Sakimoto; Jun Shoji; Ai Yamada; Mitsuru Sawa // Japanese Journal of Ophthalmology;Sep2007, Vol. 51 Issue 5, p343 

    Abstract Purpose  To investigate gelatinase [matrix metalloproteinase (MMP)-2 and MMP-9] expression in the tear fluid of patients with recurrent corneal erosion (RCE). Methods  Eleven patients with RCE, three patients with traumatic corneal erosion, and 10 control individuals were...

  • Evaluation of Total and Allergen-Specific Secretory IgA in Tears of Allergic Conjunctival Disease Patients. Noriko Inada; Jun Shoji; Mai Hoshino; Mitsuru Sawa // Japanese Journal of Ophthalmology;Sep2007, Vol. 51 Issue 5, p338 

    Abstract Purpose  To investigate the variations in total secretory IgA (sIgA) and house dust mite (HDM)-specific sIgA antibodies in tears of patients with allergic conjunctival disease (ACD). Methods  The subjects comprised 40 patients (40 eyes) with ACD and 21 healthy individuals...

  • OPHTHALMOLOGY. Alwitry, Amar // Pulse;4/19/2007, Vol. 67 Issue 15, p56 

    An interview with specialist registrar in opthalmology Amar Alwitry is presented. Alwitry stressed that the eyes may water, as the cornea dries up that lacrimal gland releases a big bolus of reflex tears that caused intermittent watering. Schirmer's test are being used by hospitals in assessing...

  • Effect of intravitreal aflibercept injection for age-related macular degeneration with a retinal pigment epithelial tear refractory to intravitreal ranibizumab injection. Ayaka Fujii; Hisanori Imai; Michiko Kanai; Atsushi Azumi // Clinical Ophthalmology;2014, Vol. 8, p1199 

    Background: The purpose of this study was to evaluate the effects of intravitreal aflibercept injection for age-related macular degeneration (AMD) with a retinal pigment epithelial (RPE) tear after intravitreal ranibizumab injection (IVR) which finally became resistant to additional IVR....

  • Education: Pictorial case study - Red eye with unaffected vision. Watkins, Jean // GP: General Practitioner;12/9/2013, p8 

    The author discusses the case of a patient with clearly defined eye discoloration. The patient showed no history of recent injury and was not taking anticoagulants. Eye examination showed his vision to be unaffected and there were no other abnormalities present. According to the author, any...

  • Journal Abstracts.  // Indian Journal of Ophthalmology;Mar2005, Vol. 53 Issue 1, p81 

    Presents abstracts of several studies on ophthalmology. "Spectrum of Fungal Keratitis in North India";"HSV-1 DNA in Tears and Saliva of Normal Adults";"A Randomized Clinical Trial of Treatments for Convergence Insufficiency in Children."

  • Focus on Tear Replacement Therapy. Kabat, Alan G. // Review of Optometry;8/15/2006, Vol. 143 Issue 8, Special section p6 

    The article focuses on the replacement therapy of dry eye, which is one of the most poorly understood and under-diagnosed conditions in the U.S. Artificial tears comprise the first line of defense against dry eye. Most artificial tear products use a demulcent component to impart lubrication and...

  • Topical allergy agents keep ocular surface safe. Groves, Nancy; Pflugfelder, Stephen C.; Gomes, Paul; Ousler, George // Ophthalmology Times;8/15/2006, Vol. 31 Issue 16, p20 

    The article discusses a study in an animal model that reveals disparities in the drying effects of two topical ocular antihistamines in the United States. The study reveals that mice receiving epinastine had higher mean tear volumes than olopatadine-treated mice. The researchers also discovered...

  • Dry eye symptoms correlated to non-ocular conditions. Kahl, Kristie L. // Ocular Surgery News;11/10/2015, Vol. 33 Issue 21, p38 

    The article discusses the study concerning the correlation of dry eye signs and symptoms to non-ocular conditions rather than tear film parameters. According to physician Anat Galor, dry eye symptoms were observed in patients on artificial tears and anti-inflammatory therapies. Approaches for...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics