Guicciardi, M. E.; Gores, G. J.
July 2005
Gut;Jul2005, Vol. 54 Issue 7, p1024
Academic Journal
The article focuses on apoptosis. Apoptosis represents the physiological way to eliminate excessive cells during embryogenesis and tissue remodeling. Apoptosis, however, is also an essential feature of a wide variety of acute and chronic diseases, including liver diseases. Excessive apoptosis has, indeed, been identified in acute and chronic viral hepatitis, alcoholic and non-alcoholic hepatitis, cholestatic liver disease, Wilson's disease and graft versus host disease. Sustained apoptosis has also been linked with the development of hepatic fibrosis.


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