Insulin resistance and steatosis in hepatitis C virus infection

Zekry, A.; McHutchison, J. G.; Diehl, A. M.
July 2005
Gut;Jul2005, Vol. 54 Issue 7, p903
Academic Journal
The article discusses insulin resistance (IR) and steatosis in hepatitis C virus (HCV) infection. Steatosis in patients with genotype 1 infection is increasingly recognized as a component of the metabolic syndrome, a condition invariably associated with IR. In support, host factors such as age, body mass index and central obesity have been shown to correlate with the development of steatosis in genotype 1 infected patients. In light of current knowledge of the implications of steatosis and IR in the liver disease, the importance of lifestyle changes need to be an emphasized in treating HCV infected patients.


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