Bordetella pertussis: the intersection of genomics and pathobiology
- Bordetella Pertussis Infections in Vaccinated and Unvaccinated Adolescents and Adults, as Assessed in a National Prospective Randomized Acellular Pertussis Vaccine Trial (APERT). Greene, Carolyn M.; Kyaw, Moe H.; Ray, Susan M.; Schaffner, William; Lynfield, Ruth; Barrett, Nancy L.; Long, Christine; Gershman, Ken; Pilishvili, Tamar; Roberson, Angela; Zell, Elizabeth R.; Whitney, Cynthia G.; Bennett, Nancy M. // Clinical Infectious Diseases;7/15/2006, Vol. 43 Issue 2, p151
Background. Acellular pertussis (aP) booster immunizations have been recommended for adolescents and older persons to enhance long-term protection and to possibly reduce community transmission of infections. Methods. This was a multicenter, randomized, double-blind vaccine trial in which...
- WHOOPING COUGH makes its return. Schweon, Steven // RN;Feb2005, Vol. 68 Issue 2, p32
Provides information on whooping cough and discusses the benefit of early detection and vaccination in stopping its transmission. Identification of the bacterium Bordetella pertussis as the cause of the communicable respiratory disease; Observation of a rise in the incidence of whooping cough...
- Manifestations of Pertussis in Immunized Children and Adults. Kirchner, Jeffrey T. // American Family Physician;11/1/1999, Vol. 60 Issue 7, p2148
Provides information on the prevalence and incidence of Bordetella pertussis (B. pertussis) infections in adults. Clinical presentation and course of B. pertussis infection among immunized persons; Diagnosis and treatment of B. pertussis infection.
- Whooping cough vaccine `should be replaced'. Brown, Phyllida // New Scientist;10/23/93, Vol. 140 Issue 1896, p7
Reports on the use of acellular vaccines as replacement for whooping cough vaccine or pertussis. Existing whole-cell vaccine based on a suspension of the whole, killed bacterium, Bordetella pertussis; Limitations of the United States Food and Drug Administration-licensed acellular vaccine.
- Reactions after pertussis vaccine: a manufacturer's experiences and difficulties since 1964. Griffith, A.H. // British Medical Journal;4/1/1978, Vol. 1 Issue 6116, p809
Pertussis vaccines vary in quality, safety, and efficacy according to the production strains of Bordetella pertussis, the method of manufacture, and quality control procedures. It is therefore not justifiable to combine information on the incidence, nature, and severity of reactions after all...
- Editorial Commentary: Accounting for Pertussis. DeMaria, Alfred // Clinical Infectious Diseases;Jun2012, Vol. 54 Issue 12, p1736
An introduction is presented in which the editor discusses the article on pertussis vaccines.
- Resistance to Whooping Cough Vaccine. Luntz, Stephen // Australasian Science;Apr2010, Vol. 31 Issue 3, p4
The article reports on the study of Professor Ruiting Lan of the University of New South Wales (NSW) School of Biotechnology and Biomolecular Sciences which reveals that two strains of Bordetella pertussis or whooping cough are resistant to the widely used acellular vaccine.
- Genetic and antigenic analysis of Bordetella pertussis isolates recovered from clinical cases in Ontario, Canada, before and after the introduction of the acellular pertussis vaccine. Tsang, Raymond S. W.; Sill, Michelle L.; Martin, Irene E.; Jamieson, Frances // Canadian Journal of Microbiology;Oct2005, Vol. 51 Issue 10, p887
Sixty-eight Bordetella pertussis isolates (obtained between 1994 and 2004 from the province of Ontario in Canada) were compared by the following phenotypic and genetic analyses: serotyping; pulsed-field gel electrophoresis; and partial DNA sequence analysis of their pertactin, pertussis toxin,...
- Protection against pertussis by immunisation. McKendrick, M.W.; Gully, P.R.; Geddes, A.M. // British Medical Journal;11/22/1980, Vol. 281 Issue 6252, p1390
Examines the efficacy of pertussis immunization for the protection against Bordetella pertussis infection. Severity of the illness in infants; Epidemiology of pertussis; Protection against the complication of the disease.