Wilson, Harold
December 1939
Australian Journal of Experimental Biology & Medical Science;Dec1939, Vol. 17 Issue 4, p393
Academic Journal
Spreading power has been shown in culture filtrates of 16 strains of haemolytic streptococcus; it was absent from culture filtrates of 11 other strains. Consistent results have been obtained from repeated tests of strains which either showed or did not show spreading power. Haemolytic streptococci have been found in the throats of half the patients with faucial diphtheria. Nearly one-fifth of the strains isolated were isolated anaerobically only; more than half belonged to group A. The spreading power of the haemolytic streptococci was evidently not related to the severity of the faucial diphtheria. Haemolytic staphylococci were found in relatively more patients with severe than with mild faucial diphtheria. The killing-power of C. diphtheriac was not enhanced in the presence of the spreading factor derived from streptococci or staphylococci, although the lesion which followed the intradermal injection of diphtheria toxin or of toxigenic C. diphtheriac was increased in width when the toxin or C. diphtheria was injected together with the spreading factor.


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