Fundoplication eliminates chronic cough due to non-acid reflux identified by impedance pH monitoring

Mainie, I.; Tutuian, R.; Agrawal, A.; Hila, A.; Highland, K. B.; Adams, D. B.; Castell, D. O.
June 2005
Thorax;Jun2005, Vol. 60 Issue 6, p521
Academic Journal
The symptoms of extra-oesophageal gastro-oesophageal reflux disease (GORD) (such as chronic and hoarseness) are traditionally more difficult to treat than typical GORD symptoms (heartburn and regurgitation). Patients with extra-oesophageal manifestations may require longer and higher doses of acids suppressive therapy. In patients not responding to acid suppressive therapy the physician faces a dilemma as to whether the symptoms are due to ongoing acid-reflux, non-acid reflux, or not associated with reflux. We report the case of a 45 year old woman with a history of a chronic cough referred for fundoplication after documenting her symptoms were associated with non-acid reflux using multichannel intraluminal impedance and pH (MII-pH).


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