TITLE

PRO: Maintenance Therapy Is Superior to Episodic Therapy

AUTHOR(S)
Lichtenstein, Gary R.
PUB. DATE
July 2005
SOURCE
American Journal of Gastroenterology;Jul2005, Vol. 100 Issue 7, p1433
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article debates on the use if infliximab in the treatment of Crohn's disease. The primary goals of pharmacological intervention in Crohn's disease are to improve the patient's quality of life, reduce the risk of Crohn's disease-related complications and avoid surgical intervention. The presence of antibodies to infliximab is associated with decreased clinical responsiveness and an increased risk of infusion reactions, albeit with low positive predictive value. Maintenance therapy is less immunogenic than episodic therapy, as demonstrated by results from the clinical trials.
ACCESSION #
17342089

 

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