Predictive value of death certification in the case ascertainment of epilepsy

Bell, G. S.; Gaitatzis, A.; Johnson, A. L.; Sander, J. W.
December 2004
Journal of Neurology, Neurosurgery & Psychiatry;Dec2004, Vol. 75 Issue 12, p1756
Academic Journal
Objectives: Death certificates are an unreliable source of information on cause of death, and mortality due to epilepsy can thus be underestimated. Methods: We investigated people with epilepsy who had died, and attempted to identify factors that influence inclusion of epilepsy on the death certificate; eight factors were hypothesised and entered into a univariate logistic regression model. Results: Epilepsy was on the death certificate of 16/243 (7%) people who had had epilepsy. Factors that influenced whether or not epilepsy appeared on the certificate were seizure frequency, anti epileptic drug treatment, cause of death, and certifying physician. Factors that did not seem to influence the inclusion of epilepsy were presence of convulsive seizures, occurrence of seizures during follow up, and age at death. Conclusions: We have estimated the degree of unreliability of death certificates (as currently used in the UK) as a source of information on cause of death in epilepsy. We have found that epilepsy may not appear on death certificates even if people had active epilepsy.


Related Articles

  • Lacosamide as add-on in brain tumor-related epilepsy: preliminary report on efficacy and tolerability. Maschio, M.; Dinapoli, L.; Mingoia, M.; Sperati, F.; Pace, A.; Pompili, A.; Carapella, C.; Vidiri, A.; Muti, P. // Journal of Neurology;Nov2011, Vol. 258 Issue 11, p2100 

    Lacosamide (LCM) is an antiepileptic drug (AED) that has demonstrated a good efficacy in controlling seizures as an add-on in adult epilepsy. To date, there have been no studies on LCM in patients with brain tumor-related epilepsy (BTRE). To evaluate efficacy and tolerability of LCM as an add-on...

  • Depression as a Factor Affecting the Quality-of-Life Assessment in Patients with Epilepsy. Mikhailov, V. A.; Tabulina, S. D.; Gromov, S. A. // International Journal of Mental Health;Fall2004, Vol. 33 Issue 3, p63 

    The article discusses the depression as a factor affecting the quality-of-life assessment in patients with epilepsy. Forms of manifestations in emotional disorders in patients with epilepsy; Determination on the affective and emotional-personality disorders in epilepsy according to Wasserman,...

  • Epilepsy in Philippine language and dialects. Casanova-Gutierrez, Josephine // Neurology Asia;Jun2012, Vol. 17 Issue 2, p83 

    In the Philippines, English and Filipino (standardized Tagalog) are widely used for media and education. "Epilepsy" and "kumbulsyon" are commonly used terms; "epilepsy" carries a negative connotation based on a local unpublished epilepsy knowledge, attitude and perception survey. Several popular...

  • Perception and attitude to epilepsy among teachers in primary, secondary and tertiary educational institutions in middle belt Nigeria. Sanya, E. O.; Salami, T. A. T.; Goodman, O. O.; Buhari, O. I. N.; Araoye, M. O. // Tropical Doctor;Jul2005, Vol. 35 Issue 3, p153 

    Compared with the disability associated with repeated seizures or side-effects of antiepileptic medications, the social stigma associated with epilepsy is often a major handicap to people living with this condition. This study therefore looked at the knowledge, attitude and perception of...

  • The Basics of How to Reveal Epilepsy. Mittan, Robert J. // Exceptional Parent;Jun2009, Vol. 39 Issue 6, p48 

    The article discusses the basics of how to reveal epilepsy to others including additional advantages received. It mentions that epilepsy is common to the person whose family has also a background of the disability. It notes that people think that talking about epilepsy is a matter of educating...

  • Association of demographic, clinical and treatment variables with quality of life of patients with epilepsy in Greece. Piperidou, Charitomeni; Karlovasitou, Anna; Triantafyllou, Nikolaos; Dimitrakoudi, Evagelia; Terzoudi, Aikaterini; Mavraki, Eleni; Trypsianis, Grigorios; Vadikolias, Konstantinos; Heliopoulos, Ioannis; Vassilopoulos, Dimitrios; Balogiannis, Stavros // Quality of Life Research;Sep2008, Vol. 17 Issue 7, p987 

    The aim was to study the influence of patients’ age, frequency and type of seizures, disease duration, number of AEDs and use of benzodiazepines on the quality of life of patients with epilepsy. We consecutively identified 223 patients with epilepsy who attended the epilepsy outpatient...

  • Collaboration with the epilepsy patient. Eggers, Walter // Practical Neurology;Apr2005, Vol. 5 Issue 2, p118 

    This article is a patient's first-person account of drug therapy for epileptic seizures, written not for fellow patients but for physicians who treat epilepsy. The purpose of drug therapy is to control seizures. Physicians whose sole purpose is to control seizures can follow a simple protocol....

  • Neural Network-Based Computer-Aided Diagnosis in Classification of Primary Generalized Epilepsy by EEG Signals. Oğulata, Seyfettin Noyan; Şahin, Cenk; Erol, Rızvan // Journal of Medical Systems;Apr2009, Vol. 33 Issue 2, p107 

    Epilepsy is a disorder of cortical excitability and still an important medical problem. The correct diagnosis of a patient’s epilepsy syndrome clarifies the choice of drug treatment and also allows an accurate assessment of prognosis in many cases. The aim of this study is to classify...

  • Analysis of ictal semiology: contralateral tonic activity associated with ipsilateral automotor seizure in temporal lobe epilepsy. Cheng-qu Zhang; Xue-feng Wang; Zu-chun Huang; Lun-shan Xu // Neurology Asia;Jun2012, Vol. 17 Issue 2, p109 

    Ictal semiology is essential for the pre-operative evaluation of candidates for epilepsy surgery. We propose an ictal sign of temporal lobe epilepsy (TLE) termed tonic-automotor (TA), defined as contralateral tonic spasm of upper limb associated with ipsilateral hand automotor seizure and often...


Read the Article


Sign out of this library

Other Topics