TITLE

Recent advances in peptide chiral selectors for electrophoresis and liquid chromatography

AUTHOR(S)
Bluhm, Louis; Huang, Junmin; Li, Tingyu
PUB. DATE
June 2005
SOURCE
Analytical & Bioanalytical Chemistry;Jun2005, Vol. 382 Issue 3, p592
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The application of peptides in chiral separations using techniques such as capillary electrophoresis (CE), electrokinetic capillary chromatography (EKC) and liquid chromatography is the focus of this review. Methods for finding peptide selectors using combinatorial library approaches are discussed, as well as recent advances in the use of peptides as general chiral selectors for electrophoresis and liquid chromatography. One example shows the effectiveness of polymeric dipeptide surfactants as general chiral selectors for electrophoresis. Another example shows the versatility of oligoproline chiral stationary phases, exhibiting resolution for a number of racemic analytes comparable to other well-established chiral stationary phases.
ACCESSION #
17211493

 

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