TITLE

The time to eradicate gastric cancer is now

AUTHOR(S)
Graham, D. Y.; Shiotani, A.
PUB. DATE
June 2005
SOURCE
Gut;Jun2005, Vol. 54 Issue 6, p735
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Worldwide gastric cancer remains one of the most common cancers, killing upwards of one million people each year. While the molecular pathogenesis remains unclear, infection with the bacterium Helicobocter pylon is considered a "necessary but not sufficient" cause, not surprisingly as gastric cancer has long been known to be associated with atrophic gastritis. Eradication of H pylori is expected to virtually eliminate gastric cancer and H pylon associated peptic ulcer within approximately 40 years and thus reduce overall mortality. In the USA, the incidence of gastric cancer in the general population is low, reflecting the change in the pattern of gastritis from atrophic to non- atrophic and in the low and decreasing prevalence of H pylon infection in the middle and upper classes. However, the plan for eradication of this important pathogen must be considered within the context of the prevalence and outcome within specific populations.
ACCESSION #
17176759

 

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