Review: Some therapies for treating the irritable bowel syndrome may be effective for symptom improvement: COMMENTARY

Primack, Brian A.
May 2005
ACP Journal Club;May/Jun2005, Vol. 142 Issue 3, p78
Academic Journal
This article presents information related to therapies for treating the irritable bowel syndrome (IBS) which may be effective for symptom improvement. In addition to accounting for 28% of problems seen in gastroenterology practice, IBS is the second leading cause of absenteeism from work or school. IBS is a particularly complex topic to study via meta-analysis, at least in part because of its poorly understood pathophysiology and myriad treatment options. When judged by the original Manning criteria, IBS prevalence estimates can be eleven times higher than the more stringent Rome criteria.


Related Articles

  • Reports of “Satisfactory Relief” by IBS Patients Receiving Usual Medical Care Are Confounded by Baseline Symptom Severity and Do Not Accurately Reflect Symptom Improvement. Whitehead, William E.; Palsson, Olafur S.; Levy, Rona L.; Feld, Andrew D.; VonKorff, Michael; Turner, Marsha // American Journal of Gastroenterology;May2006, Vol. 101 Issue 5, p1057 

    BACKGROUND: Treatment trials for irritable bowel syndrome (IBS) usually define a responder as a patient who reports satisfactory relief or adequate relief of symptoms at the end of the trial. However, these measures have not been adequately validated. AIMS: (1) Compare a binary satisfactory...

  • Randomized Clinical Trial: The Clinical Effects of Herb-Partitioned Moxibustion in Patients with Diarrhoea-Predominant Irritable Bowel Syndrome. Yu-xia Ma; Xiao Liu; Cun-zhi Liu; Lin-peng Wang; Gang Guo; Dong-qing Du; Zhi-lei Wang; Hong Ma; Ping Qi; Zhao-feng Li; Yan-ping Guo; Hua-qiang Yi; Shu-zhong Gao // Evidence-based Complementary & Alternative Medicine (eCAM);2013, Vol. 2013, p1 

    Objective. To explore the efficacy of Herb-partitioned moxibustion in treating IBS-D patients. Method. 210 IBS-D patients were randomly assigned on a 3 : 3 : 2 basis to group HM, group FM, or group PB for 4-week treatment. The change of GSRS total score at weeks 4 and 8, the changes of GSRS...

  • Visceral Afferent Hypersensitivity in Irritable Bowel Syndrome--Evaluation by Cerebral Evoked Potential After Rectal Stimulation. Sinhamahapatra, Pradyot; Saha, Shankar Prasad; Chowdhury, Abhijit; Chakrabarti, Susil Kumar; Ghosh, Alakendu; Maiti, Bibekananda // American Journal of Gastroenterology;Jul2001, Vol. 96 Issue 7, p2150 

    OBJECTIVES: Gut hypersensitivity has been shown to be present in irritable bowel syndrome. The current study sought to determine the involvement or hypersensitivity of the gut afferents, objectively, by recording cerebral evoked potential after rectal stimulation. METHODS: In 13 patients with...

  • Reflux, IBS rates higher in CD.  // GIG Newsletter;Spring2011, Vol. 34 Issue 2, p43 

    The article reports on the high incidence of reflux and irritable bowel syndrome among patients with celiac disease based on a study published in a 2011 issue of "European Journal of Gastroenterology."

  • A REVIEW ON RECENT APPROACHES IN TREATMENT OF IRRITABLE BOWEL SYNDROME. Chandra, Suresh; Maurya, Mangla; Sahu, Shachi // Pharma Science Monitor;Apr2013, Vol. 4 Issue 2, p3844 

    Irritable bowel syndrome (IBS) is the most prevalent functional gastrointestinal disorder noted in the general population worldwide characterized by abdominal pain associated with abnormal bowel movement without any clinically identifiable structural or biochemical abnormality. The...

  • Treatment of Irritable Bowel Syndrome: New Modalities for a New Millennium. Olden, Kevin W. // American Journal of Gastroenterology;Apr2000, Vol. 95 Issue 4, p863 

    Comments on a study by I. Heymann-Mönnikes et al regarding the treatment of irritable bowel syndrome. Medicines used in the study; Number of sessions included in the standardized multicomponent behavioral therapy described by the researchers; Measures used in the physiological evaluation of...

  • Adrenergic β2-Receptors Mediates Visceral Hypersensitivity Induced by Heterotypic Intermittent Stress in Rats. Zhang, Chunhua; Rui, Yun-Yun; Zhou, Yuan-Yuan; Ju, Zhong; Zhang, Hong-Hong; Hu, Chuang-Ying; Xiao, Ying; Xu, Guang-Yin // PLoS ONE;Apr2014, Vol. 9 Issue 4, p1 

    Chronic visceral pain in patients with irritable bowel syndrome (IBS) has been difficult to treat effectively partially because its pathophysiology is not fully understood. Recent studies show that norepinephrine (NE) plays an important role in the development of visceral hypersensitivity. In...

  • Editorial: Fecal Granins in IBS: Cause or Indicator of Intestinal or Colonic Irritation? Camilleri, Michael // American Journal of Gastroenterology;Mar2012, Vol. 107 Issue 3, p448 

    Ohman et al. report increased fecal granins in patients with irritable bowel syndrome (IBS). Several interesting questions arise from their observations. Are the granins a cause of the pathophysiology or phenotype in IBS? Is the elevation of granins specific to IBS? What is the cause of...

  • Caring for children with IBD. Black, Peter // Gastrointestinal Nursing;Nov2008, Vol. 6 Issue 9, p3 

    The author reflects on caring for children with irritable bowel syndrome (IBD). He explains that the problem with relying on evidence that has been generated on adult populations is that the safety and efficacy profiles of medications may be different for children than adults because of their...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics