Review: Some therapies for treating the irritable bowel syndrome may be effective for symptom improvement

May 2005
ACP Journal Club;May/Jun2005, Vol. 142 Issue 3, p78
Academic Journal
This article presents information related to therapies for treating the irritable bowel syndrome (IBS) which may be effective for symptom improvement. Fully published studies in the English language were selected if they were placebo-controlled studies on the treatment of IBS. 5 trials showed a benefit of alosetron for relieving IBS symptoms in patients with diarrhea only. 4 trials showed a benefit of tegaserod for relieving IBS symptoms in patients with constipation, but the studies were mainly done in women.


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