Review: Intravenous metoclopramide is better than placebo for reducing pain in acute migraine in the emergency department: COMMENTARY

Loder, Elizabeth W.
May 2005
ACP Journal Club;May/Jun2005, Vol. 142 Issue 3, p77
Academic Journal
This article presents information related to the drug Metoclopramide that avoids many perceived or actual liabilities of other current treatment choices for acute migraine. It also provides relief of pain and other such migraine-associated symptoms such as nausea and vomiting. Although the results show a reduction in pain that favors metoclopramide over placebo, the duration of effect and rate of headache relapse are not known. However, metoclopramide alone does provide definitive treatment for some patients. 3 of 4 patients on average will require alternative or adjunctive treatment.


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