Review: Intravenous metoclopramide is better than placebo for reducing pain in acute migraine in the emergency department

May 2005
ACP Journal Club;May/Jun2005, Vol. 142 Issue 3, p77
Academic Journal
This article presents information related to patients with acute migraine. Randomized controlled trials (RCTs) that compared parenteral metoclopramide with control (placebo, other antiemetics (AEs), non-AEs, or other antimigraine (AM) regimens in adults with an acute migraine, distinguished migraine from other types of headaches, and were done in an emergency department (ED) or headache clinic. There was a complete relief of headache, significant reduction in headache pain, and reduction in headache pain on the basis of a 10-cm visual analogue scale (VAS).


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