Intradermal injection of reduced-dose influenza vaccine was immunogenic in young adults

May 2005
ACP Journal Club;May/Jun2005, Vol. 142 Issue 3, p69
Academic Journal
This article cites a medical research which sought to find out whether an intradermal injection of one fifth the standard intramuscular dose of a commercial influenza vaccine is as immunogenic as the standard-dose intramuscular injection in young adults. The study was based on a randomized controlled trial. The intradermal and intramuscular groups did not differ in hemagglutination inhibition response or fold increase in titer for the A/New Caledonia or B/Hong Kong strains on day 21. The intramuscular group had a better response to the B/Hong Kong strain on day 42.


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