TITLE

Review: Bupropion and nortriptyline each increase smoking cessation rates: COMMENTARY

AUTHOR(S)
Prochazka, Allan V.
PUB. DATE
May 2005
SOURCE
ACP Journal Club;May/Jun2005, Vol. 142 Issue 3, p67
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
This article comments on the previous review on the effect of bupropion and nortriptyline on smoking cessation rates. The detailed review by previous researchers showed that only bupropion and, to a lesser extent, nortriptyline have strong evidence for effectiveness. SSRIs are not effective. All of these agents are useful for treatment of depression, which suggests that different neurochemical actions contribute to success in smoking cessation and that this success is not simply the result of treating subclinical depression. Both bupropion and nortriptyline interact with the dopamine and norepinephrine systems in the brain, whereas SSRIs do not.
ACCESSION #
17116530

 

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