Diuretic-based therapy reduced cardiovascular mortality in older patients with isolated systolic hypertension and diabetes: COMMENTARY
- Stable plasma magnesium and potassium status in essential hypertensive patients with normal renal function under therapy with the renin inhibitor aliskiren. Kisters, K.; Gremmler, B.; Nguyen, M. Q.; Tokmak, F. // Trace Elements & Electrolytes;2011 2nd Quarter, Vol. 28 Issue 2, p113
Lowered Mg++ stores in humans seem to be involved in the pathogenesis of essential hypertension. However, some antihypertensive drugs (e.g. in particular diuretics) can additionally decrease plasma or intracellular Mg-H- stores. In this context the role of the new antihypertensive renin...
- Where do the new agents fit in hypertension management? Kopes-Kerr, Colin P. // American Family Physician;6/1/1996, Vol. 53 Issue 8, p2427
Editorial. Recommends going back to simple, inexpensive, once-daily diuretics for the treatment of most patients with hypertension. Other drugs for hypertension; Reasons behind the author's change of view; Principal advantage of expanded range of equipotent antihypertensive drugs.
- Six years after ALLHAT, diuretic use still lags. // Pharmacy Today;Jan2009, Vol. 15 Issue 1, p1
The article reports that the use of generic diuretics has not increased significantly. According to a study, conducted in 2002, generic diuretics are more effective in the treatment of high blood pressure compared to newer and expensive treatments. The Antihypertensive and Lipid-Lowering...
- Calcium channel antagonists + diuretics not a hearty combination? // Reactions Weekly;1/8/2005, Issue 1033, p3
Focuses on a study on the effects of combined therapy with calcium channel antagonists and diuretics on women. Methodology of the study; Number of respondents who were receiving combined therapy; Comparison between the effects of monotherapy and combined therapy on women.
- Clinical predictors of the response to short-term thiazide treatment in nondiabetic essential hypertensives. Huang, C.-C.; Leu, H.-B.; Wu, T.-C.; Lin, S.-J.; Chen, J.-W. // Journal of Human Hypertension;May2008, Vol. 22 Issue 5, p329
Blood pressure (BP) response to diuretics is varied in hypertensive patients. This study aimed to identify the patients who may respond better or worse to thiazide diuretics. Nondiabetic patients with treated or untreated hypertension were evaluated if they did not take diuretics and their...
- Continuous use of combined contraceptive pill minimises vaginal bleeding. // BMJ: British Medical Journal (International Edition);7/26/2003, Vol. 327 Issue 7408, p172
Offers the results of a study in the use of combined oral contraceptive pills and their effectiveness in reducing vaginal bleeding. Details of the women were tested; Number of months in which most women taking the combination oral contraceptive pills on a continuous basis will not have any...
- Diuretics should be first line treatment for hypertension. // BMJ: British Medical Journal (International Edition);8/30/2003, Vol. 327 Issue 7413, p458
Presents an article offering evidence as to why diuretics should be used as the first line treatment of hypertension. Reasons why; Details of the antihypertensive and lipid-lowering treatment to prevent heart attack trial (ALLHAT).
- Try this low-dose combination for patients with mild-to-moderate hypertension. // Modern Medicine;Jul94, Vol. 62 Issue 7, p22
Focuses on a study by Chrysant and colleagues proving that using lisinopril and hydrochlorothiazide together in low doses may be the best choice for treating hypertension. Optimalization of antihypertensive efficacy and tolerability; Recommended dosage; Absence of effects on heart rate.
- Thiazide-Like/Calcium Channel Blocker Agents: A Major Combination for Hypertension Management. Safar, M.; Blacher, J. // American Journal of Cardiovascular Drugs;Dec2014, Vol. 14 Issue 6, p423
In recent years, treatment strategies for hypertension have often focused on combination therapies that include diuretics and renin angiotensin aldosterone system blockers such as angiotensin-converting enzyme inhibitors or angiotensin receptor blockers. However, in clinical practice, a...