Candesartan reduced cardiovascular mortality and morbidity in chronic heart failure with low ejection fraction

May 2005
ACP Journal Club;May/Jun2005, Vol. 142 Issue 3, p60
Academic Journal
This article cites a medical study which reports that candesartan reduced cardiovascular mortality and morbidity in chronic heart failure with low ejection fraction. Subanalysis of two randomized placebo-controlled trials, one adding candesartan in patients already taking angiotensin-converting enzyme (ACE) inhibitors and the other adding candesartan in patients who could not tolerate ACE inhibitors, was made. In patients with symptomatic chronic heart failure and reduced left-ventricular ejection fraction, candesartan reduced cardiovascular mortality, heart failure hospitalizations, and all-cause mortality, but increased adverse events.


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