A prophylactically implanted cardioverter defibrillator did not reduce all-cause mortality after a recent myocardinal infarction

May 2005
ACP Journal Club;May/Jun2005, Vol. 142 Issue 3, p58
Academic Journal
This article discusses a medical case wherein a prophylactically implanted cardioverter defibrillator did not reduce all-cause mortality after a recent myocardial infarction. 674 patients 18 to 80 years of age who had recently had an MI and had a left ventricular ejection fraction ≤0.35. Patients were also required to have a standard deviation of normal-to-normal RR intervals ≤70 msec or a mean RR interval ≤750 msec (heart rate ≥80 beats/min) over a 24-hour period measured ≥3 days after the infarction. Exclusion criteria included congestive heart failure or New York Heart Association class IV, noncardiac disease that limited life expectancy, and coronary artery bypass grafting after the qualifying infarction scheduled ≤4 weeks after randomization.


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