TITLE

Weighted event rates

AUTHOR(S)
Werre, Stephen R.; Walker-Dilks, Cindy
PUB. DATE
May 2005
SOURCE
ACP Journal Club;May/Jun2005, Vol. 142 Issue 3, pA10
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article reports that the main factor in determining the weight for a trial is the number of events, which in turn depends on sample size, the event rate, and duration of follow-up. Trials with more events get more weight. The number of events and total number of patients in each of the treatment arms are combined into a single statistical concept called variance. Variances can be calculated for the event rates in each of the treatment arms, for the risk difference between the treatment groups, or for the relative risk. A good example of a weight would then be 1/variance. Computer software is available to do most of the computations (e.g., RevMan, SAS, and Stata).
ACCESSION #
17116509

 

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