Gaisböck's Syndrome: Its Hematologic, Biochemical and Hormonal Parameters

Stefanini, Mario; Urbas, John V.; Urbas, John E.
July 1978
Angiology;Jul1978, Vol. 29 Issue 7, p520
Academic Journal
The syndrome of plethora without splenomegaly% leukocytosis, or thrombocytosis was described by Gaisböck in 1 905. it was reevaluated in 25 patients through the study of numerous hematologic and biochemical part meters. Statistically significant findings included mild obesity: elevation of blood pressure (especially diastolic); decrease in plasma volume with relative increase in red cell count, hemoglobin, hematocrit, viscosity of blood, elevation of plasma proteins, serum cholesterol, triglycerides, uric acid, and plasma renin: and increased excretion of urinary sodium. The reduction in plasma volume seemed related to the elevation of the diastolic blood pressure, arid favorable through temporary therapeutic results were produced by sonic antihypertensive agents. The elevation of serum cholesterol, triglycerides, and uric acid, he increased blood Viscosity, and the elevated plasma renin were reminescent of he biochemical changes observed in sonic instances of hypertension and atherosclerosis disease. They may explain why patients with the Gaishöck's syndrome belong to the high risk group of hypertensive individuals who often develop cardiovascular complications. While its' long-term effects remain to be evaluated. treatment with nondiuretic antihypertensive drugs may help reduce the incidence of these complications.


Related Articles

  • Determinants of New-Onset Diabetes Among 19,257 Hypertensive Patients Randomized in the Anglo-Scandinavian Cardiac Outcomes Trial-Blood Pressure Lowering Arm and the Relative Influence of Antihypertensive Medication. Gupta, Ajay K.; Dahlof, Bjorn; Dobson, Joanna; Sever, Peter S.; Wedel, Hans; Poulter, N. R. // Diabetes Care;May2008, Vol. 31 Issue 5, p982 

    OBJECTIVE -- The purpose of this study was to determine the baseline predictors of new-onset diabetes (NOD) in hypertensive patients and to develop a risk score to identify those at high risk of NOD. RESEARCH DESIGN AND METHODS -- Among 19,257 hypertensive patients in the Anglo-Scandinavian...

  • Hemorheologic Effects of Vasodilation in Essential Hypertension. Wysocki, Marian; Andersson, Ove K.; Persson, Bengt; Bagge, Ulf; Braide, Magnus // Angiology;Sep1996, Vol. 47 Issue 9, p869 

    Arterial hypertension is often associated with plasma volume contraction and hemoconcentration, which negatively affect the vascular flow resistance and microcirculation. Since some antihypertensive drugs can affect blood rheology, the purpose of this study was to evaluate whether acute and...

  • Correlation of Angiotensin-Converting Enzyme Gene Polymorphism with Effect of Antihypertensive Therapy by Angiotensin-Converting Enzyme Inhibitor. Xiaotao Li; Yanmei Du; Yanfang Du; Xizheng Huang // Journal of Cardiovascular Pharmacology & Therapeutics;Mar2003, Vol. 8 Issue 1, p25 

    The article presents information on the correlation of angiotensin-converting enzyme gene polymorphism with effect of antihypertensive therapy by angiotensin-converting enzyme inhibitor. The insertion/deletion (I/D) polymorphism in intron 16 of the angiotensin-converting enzyme (ACE) gene...

  • Blood pressure control: still an elusive target.  // American Journal of Hypertension;Feb2008, Vol. 21 Issue 2, p126 

    The article introduces two articles published within the issue, including an article titled "Hypertension Control at Physicians' Offices in the United States" and an article titled "Predictors of Persistence With Antihypertensive Therapy: Results From the NHANES."

  • Blood Pressure Lowering Effect of an Olive Leaf Extract (Olea europaea)in L-NAME Induced Hypertension in Rats. Khayyal, Mohamed T.; El-Ghazaly, Mona A.; Abdallah, Dalal M.; Nassar, Noha N.; Okpanyi, Samuel N.; Kreuter, Matthias-Heinrich // Drug Research / Arzneimittel-Forschung (Editio Cantor Verlag fur;Nov2002, Vol. 52 Issue 11, p797 

    A specially prepared olive leaf extract (EFLA 943) has been tested for its blood pressure lowering activity in rats rendered hypertensive by daily oral doses of L-NAME (N[SUPG]-nitro-L-arginine methyl ester, 50 mg/kg) for at least 4 weeks. Oral administration of the extract at different dose...

  • Hypertension and the heart. Schmieder, R E; Messerli, F H // Journal of Human Hypertension;Oct2000, Vol. 14 Issue 10/11, p597 

    It has been clearly demonstrated that left ventricular (LV) hypertrophy is a strong blood pressure independent risk factor for cardiovascular morbidity and mortality in the general population, in primary and secondary hypertension and in cardiac patients. LV hypertrophy in arterial hypertension...

  • Elasticity Indices of Large and Small Arteries in Relation to the Metabolic Syndrome in Chinese. Ji-Yong Ge; Xin-Li Li; Hai-Feng Zhang; Qiong Xu; Min Tong; Ji-Guang Wang // American Journal of Hypertension;Feb2008, Vol. 21 Issue 2, p143 

    BACKGROUND The purpose of this study was to investigate the elasticity of large and small arteries in relation to the components of the metabolic syndrome in a Chinese population. METHODS Arterial elasticity indices were derived from pulse wave analysis based on a modified Windkessel model in...

  • Carotid sinus syndrome: Progress in understanding and management. Sutton, Richard // Global Cardiology Science & Practice;2014, Vol. 2014 Issue 2, p1 

    Carotid sinus syndrome (CSS) is a disease of the autonomic nervous system presenting with syncope, especially in older males who often have cardiovascular disease. The aetiology is unknown and epidemiological data is limited. Forty new patients/million population have been estimated to require...

  • BP of 150 adequate for older adults.  // Clinical Advisor;Dec2014, Vol. 17 Issue 12, p20 

    No abstract available.


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics