In Vitro Angiogenic Activity of RNA From Leukemic Lymphocytes

DeCarvalho, S.
July 1978
Angiology;Jul1978, Vol. 29 Issue 7, p497
Academic Journal
The article uncovers the nature of the lymphocyte factor or factors responsible for the angiogenic activity. In view of the recent renewal of interest in tumor and tissue angiogenic factor as well as in angiogenic activity by transformed lymphocytes, in addition to the intriguing angioblastic component of Lukes-Rappaport immunoproliferative syndromes, this work may point to the ribonucleic acid nature of the vessel-forming principle. Various cell-differentiating properties of RNA preparations have been repeatedly described, and thus it is not altogether surprising that lymphocyte angiogenic factor may originate in RNA.


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