TITLE

Plasminogen and Moderate Doses of Urokinase in the Treatment of Acute Pulmonary Embolism

AUTHOR(S)
Griguer, P.; Charbonnier, B.; Latour, F.; Fauchier, J. P.; Brochier, Mireille
PUB. DATE
January 1979
SOURCE
Angiology;Jan1979, Vol. 30 Issue 1, p1
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
This article focuses on the use of plasminogen and moderate doses of urokinase in the treatment of acute pulmonary embolism (PE). Urokinase (UK) at moderate doses has proved in the authors' first series of 80 patients to be as effective as urokinase at high doses in the treatment of massive or severe pulmonary embolism. Experiments have shown that 35,000 CTA units of UK per hour are enough to develop fibrinolytic activity in the plasma, resulting in the rapid lysis of artificial clots. The results of the treatment of PE vary considerably as far as mortality is concerned.
ACCESSION #
16902439

 

Related Articles

  • Should Thrombolytic Therapy Be Used in Patients with Pulmonary Embolism? Stavros Konstantinides // American Journal of Cardiovascular Drugs;2004, Vol. 4 Issue 2, p69 

    More than thirty years have passed since streptokinase was first shown to dissolve pulmonary arterial thrombi and normalize pulmonary artery pressure in patients with acute pulmonary embolism (PE). Following the initial observations, a number of controlled clinical trials confirmed that...

  • Should systemic thrombolytic therapy be considered a first-line treatment in acute pulmonary embolism? Gökalp, Orhan; Beşir, Yüksel; Eygi, Börtecin; Gökalp, Gamze; Aykan, Ahmet Çarğrı // Anatolian Journal of Cardiology / Anadolu Kardiyoloji Dergisi;Jan2015, Vol. 15 Issue 1, p82 

    A letter to the editor is presented in response to the article related to the successful treatment of a pulmonary embolism with low-dose prolonged infusion of tissue-type plasminogen activator by Ahmet Çağri Aykaii published in 2014 issue, along with the reply of the authors to the same.

  • AngioJet Rheolytic Thrombectomy Versus Local Intrapulmonary Thrombolysis in Massive Pulmonary Embolism: A Retrospective Data Analysis. Siablis, Dimitris; Karnabatidis, Dimitris; Katsanos, Konstantinos; Kagadis, George C.; Zabakis, Peter; Hahalis, George // Journal of Endovascular Therapy (Allen Press Publishing Services;Apr2005, Vol. 12 Issue 2, p206 

    Purpose: To compare the efficacy of full-dose local intrapulmonary thrombolysis (LIT) versus AngioJet rheolytic thrombectomv (ART) in the treatment of massive pulmonary embolism. Methods: A retrospective review was conducted of 8 consecutive patients (5 women; mean age 66.0±5.9 years, range...

  • Randomised Controlled Trial of Recombinant Tissue Plasminogen Activator Versus Urokinase in the Treatment of Acute Pulmonary Embolism.  // JAMA: Journal of the American Medical Association;3/10/89, Vol. 261 Issue 10, p1438 

    Discusses the abstract of a research study concerning randomized controlled trial of recombinant tissue plasminogen activator versus urokinase in the treatment of acute pulmonary embolism. Principal end points of the comparison; Complications caused by urokinase infusions on several patients.

  • THROMBOLYTIC THERAPY: DIFFERENCES BETWEEN STREPTOKINASE AND UROKINASE. Bell, William R. // Vascular Surgery;Nov/Dec1977, Vol. 11 Issue 6, p378 

    Compares the relative potency of streptokinase and urokinase as agents for thrombolytic therapy in patients with pulmonary emboli. Therapeutic regimens of streptokinase and urokinase; Biochemical properties of streptokinase and urokinase; Assessment of the therapeutic improvement after the...

  • Re-introduction of urokinase.  // WHO Drug Information;2002, Vol. 16 Issue 3, p232 

    Reports on the U.S. Food and Drug Administration's reintroduction of urokinase onto the market. Indication of the drug solely for the treatment of pulmonary embolism; Labeling information of the drug.

  • Streptokinase and Heparin in the Treatment of Pulmonary Embolism: A Randomized Comparison. Dotter, Charles T.; Seaman, Arthur J.; R�sch, Josef; Porter, John M. // Vascular Surgery;Jan/Feb1979, Vol. 13 Issue 1, p42 

    Treatment with streptokinase followed by heparin was compared on a randomized basis with treatment with heparin alone in patients with acute pulmonary embolism. The diagnosis and results of treatment were established by pulmonary angiography. Fifteen patients received streptokinase and 16...

  • Successful treatment of a pulmonary embolism with low dose prolonged infusion of tissue typed plasminogen activator in a 37 year old female in early postoperative period. Aykan, Ahmet Çağrı; Boyacı, Faruk; Hatem, Engin // Anatolian Journal of Cardiology / Anadolu Kardiyoloji Dergisi;Jun2014, Vol. 14 Issue 4, p400 

    The article presents a case study of a 37-year-old woman who was admitted with dyspnea and chest pain, diagnosed with pulmonary embolism (PE). It mentions that she was associated with proximal deep vein thrombosis extending into the right atrium, and she had major internal bleeding and...

  • Commentary: A simple prediction rule identified patients with pulmonary embolism at low risk of short term death. O'Flaherty, Martin; Gandara, Esteban // Evidence Based Medicine;Aug2006, Vol. 11 Issue 4, p121 

    The article reflects on the Aujesky rule which has identified patients with pulmonary embolism at low risk of short term death. It argues that the Aujesky rule is an accurate risk prediction tool which is useful in a wide range of settings and is a promising therapeutic decision aid. It compares...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics