The effect of subthalamic nucleus stimulation on kinaesthesia in Parkinson's disease

Maschke, M.; Tuite, P. J.; Pickett, K.; Wächter, T.; Konczak, J.; Wächter, T
April 2005
Journal of Neurology, Neurosurgery & Psychiatry;Apr2005, Vol. 76 Issue 4, p569
Academic Journal
journal article
Background: Parkinson's disease is accompanied by deficits in passive motion and limb position sense.Objective: To investigate whether deep brain stimulation of the subthalamic nucleus (STN-DBS) reverses these proprioceptive deficits.Methods and Results: A passive movement task was applied to nine patients with Parkinson's disease and bilateral chronic STN-DBS and to seven controls. Thresholds for 75% correct responses were 0.9 degrees for controls, 2.5 degrees for Parkinson's disease patients when stimulation was OFF, and 2.0 degrees when stimulation was ON.Conclusions: STN-DBS improves kinaesthesic deficits in Parkinson's disease, but does not lead to a full recovery of proprioceptive function.


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