Age and paracetamol self-poisoning
- Acetominophen Overdose Was Determined as the Most Frequent Cause of Acute Liver Failure. Ostapowicz, G.; Fontana, R. J.; Schiødt, F. V. // Annals of Internal Medicine;9/7/2004, Vol. 141 Issue 5, p380
This article reports that acetaminophen overdose was determined as the most frequent cause of acute liver failure. This article highlights a shift in the cause and prognosis in people with acute liver failure. The prospective cohort study involved 308 consecutive patients with acute liver...
- Overdose Alert: Acetaminophen. Matus, Jordan; Harrar, Sari // Prevention;Aug2003, Vol. 55 Issue 8, p164
Discusses research being done on acetaminophen. Reference to a study by William M. Lee, published in the December 17, 2002 issue of 'Annals of Internal Medicine'; Effect of acetaminophen overdose on patients with acute liver failure.
- The systemic inflammatory response syndrome is predictive of renal dysfunction in patients with non-paracetamol-induced acute liver failure. J A Leithead // Gut;Mar2009, Vol. 58 Issue 3, p443
BACKGROUND: Although renal dysfunction is a common complication of acute liver failure (ALF) with significant prognostic implications, the pathophysiological mechanisms remain unclear. The current hypothesis suggests that the renal dysfunction may mirror the hepatorenal syndrome of cirrhosis....
- Painkillers Damage Liver. // Economic Review (05318955);Jul2003, Vol. 34 Issue 7, p16
Details the results of a study on the effects of painkillers on the liver. Effect of androstanol on blocking the activity of the molecule CAR if given within an hour of an acetaminophen overdose in mice.
- Biochemical and Histopathological studies of Butea Monosperma (Lam) Taub leaves on Paracetamol induced hepatotoxicity in albino rats. Chavan Sandeep, D.; Patil Sandeep, B.; Naikwade Nilofar, S. // Journal of Pharmacy Research;2012, Vol. 5 Issue 8, p4006
Butea Monosperma (Lam) Taub (Fabeceae) has been used in variety of diseases in traditional system of medicine in India and its use for hepatic ailments is also documented. In the present study an attempt has been made to validate its Hepatoprotective activity. The methanolic and aqueous extract...
- Paracetamol overdose. // Reactions Weekly;Apr2015, Vol. 1547 Issue 1, p219
The article presents a case study of three patients who developed either hepatotoxicity and/or liver failure after acute overdose with paracetamol.
- ACUTE LIVER FAILURE IN SCOTLAND: AN OBSERVATIONAL STUDY 1992-2003. // Gut;Apr2004 Supplement 3, Vol. 53, pA92
The article presents an observational study of acute liver failure (ALF) in Scotland. Acute liver failure is an uncommon clinical problem. The causes and outcomes differ in different populations. The provision of a single liver transplantation unit in Scotland has allowed the study of acute...
- Paracetamol overdose. // Reactions Weekly;3/15/2008, Issue 1193, p22
The article describes the case of neurogenic pulmonary oedema post-haemodialysis associated with paracetamol overdose. It references a study by A. Davenport published in "NDT Plus." A 30-year-old woman developed liver failure and neurogenic pulmonary oedema after undergoing haemodialysis and...
- Liver Oxidant Stress Induced By Paracetamol Overdose. Grypioti, A. D. // Internet Journal of Pharmacology;2006, Vol. 4 Issue 2, p7
Acetaminophen (APAP, AAP) overdose can cause severe hepatotoxicity and even liver failure and hepatic centrilobular necrosis in experimental animals and humans. Despite substantial efforts over the last 30 years, the mechanism of APAP-induced liver cell injury is still not completely understood....