Development of mucoid Pseudomonas aeruginoso coincides with pulmonary deterioration in cystic fibrosis

Derry, D.
April 2005
Thorax;Apr2005, Vol. 60 Issue 4, p334
Academic Journal
The article presents a longitudinal study, which correlates acquisition of non-mucoid and mucoid phenotypes of Pseudomonas aeruginosa with respiratory symptoms, quantitative chest radiography, pulmonary function tests, and anti-pseudomonal antibodies in cystic fibrosis (CF). 56 children identified by the Wisconsin CF neonatal screening project between 1985 and 1994 were followed from diagnosis for up to 16 years. Sputum or oropharyngeal swabs were cultured at least 6 monthly.


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