TITLE

Successful labor in the course of chronic lymphocytic leukemia (CLL) and management of CLL during pregnancy with leukapheresis

AUTHOR(S)
Ali, R.; Özkalemkaş, F.; Özkocaman, V.; Bülbül-Başkan, E.; Özçelik, T.; Ozan, Ü.; Kimya, Y.; Tunalı, A.
PUB. DATE
January 2004
SOURCE
Annals of Hematology;Jan2004, Vol. 83 Issue 1, p61
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
We describe the successful management of a 30-year-old woman in the second trimester of her pregnancy with chronic lymphocytic leukemia (CLL) in stage IV by using only leukapheresis. We applied three sessions (courses) of leukapheresis throughout the pregnancy. The procedure did not have any significant adverse effect on the patient and the fetus. The patient gave birth vaginally to a healthy boy, weighing 3100 g, at 39 weeks of gestation. Seven months after delivery, Richter's syndrome developed in the patient. We conclude that leukapheresis may provide an alternative for palliative treatment to chemotherapy in pregnant patients with CLL. To our knowledge, this is the fourth reported case of CLL in pregnancy, and the first management of CLL during pregnancy with leukapheresis.
ACCESSION #
16820996

 

Related Articles

  • Chronic lymphocytic leukemia in pregnancy. Welsh, T M; Thompson, J; Lim, S // Leukemia (08876924);Jun2000, Vol. 14 Issue 6, p1155 

    Presents a study of chronic lymphocytic leukemia (CLL) in a pregnant female. Examination of peripheral blood of the pregnant woman; Repetitive infections experienced by the female during pregnancy.

  • Leukapheresis for papilloedema in chronic granulocytic leukaemia. Stirling, M.L.; Parker, A.C.; Keller, A.J.; Urbaniak, S.J. // British Medical Journal;9/10/1977, Vol. 2 Issue 6088, p676 

    Examines the leukapheresis for papilloedema in chronic granulocytic leukemia. Increase of intracranial pressure; Dilatation of the ventricular system; Infiltration of the optic nerves.

  • Collection of Philadelphia-negative peripheral blood progenitor cells in unselected patients with chronic granulocytic leukaemia. Lennard, A L; Storey, N; Dickinson, A M; Irving, J A; Rowe, D; Conn, J S; Proctor, S J // Leukemia (08876924);May98, Vol. 12 Issue 5, p746 

    Thirty unselected patients with chronic granulocytic leukaemia (CGL), age range 22-59 years, were treated with intensive chemotherapy and G-CSF to mobilize peripheral blood progenitor cells (PBPC). Chemotherapy was well tolerated and PBPC were collected by leukapheresis early during white cell...

  • Extracorporeal photopheresis as a curative treatment strategy in non epidermotropic T-cell lymphoma and large granular lymphocyte leukemia. Garban, F.; Carras, S.; Drillat, P.; Jacob, M. C.; Fabre, B.; Callanan, M.; Courby, S.; Makowski, C.; Cahn, J. Y.; Gressin, R. // Annals of Oncology;Sep2012, Vol. 23 Issue 9, p2386 

    Background To evaluate the efficacy of extracorporeal photopheresis (ECP) in noncutaneous T-cell lymphoma and large granular lymphocytes leukemia (LGL). Patients and methods We have treated 12 refractory/relapsed patients. Six peripheral T-cell lymphoma (PTCL), one T-lymphoblastic lymphoma and...

  • Chronic lymphocytic leukaemia during pregnancy: management and thoughts. Winckler, Patricia; Vanazzi, Anna; Bozzo, Maddalena; Scarfone, Giovanna; Peccatori, Fedro A. // Ecancermedicalscience;2015, Vol. 9 Issue 577-607, p1 

    Chronic lymphocytic leukaemia (CLL) is the most common leukaemia in the Western world. Despite this fact, its coexistence with pregnancy is extremely rare, with few cases reported in the literature. Given the rarity of this event, it is difficult to conduct large prospective trials to evaluate...

  • Acute lower limb ischemia as the initial symptom of acute myeloid leukemia. Kafetzakis, Alexandros; Foundoulakis, Andreas; Ioannou, Christos V.; Stavroulaki, Emilia; Koutsopoulos, Anastassios; Katsamouris, Asterios N. // Vascular Medicine;2007, Vol. 12 Issue 3, p199 

    Although coagulatory system disorders are well recognized in patients with acute leukemia, these usually present with either hemorrhagic complications or thrombosis of small vessels. Large vessel thrombosis is a very rare clinical presentation. We present a patient with previously undiagnosed...

  • Mini-ICE regimen as mobilization therapy for chronic myelogenous leukaemia patients at diagnosis. Sureda, A; Petit, J; Brunet, S; Boqué, C; Aventín, A; Martino, R; González, J R; Amill, B; Larriba, I; Blanco, A; Martín-Henao, G A; Sierra, J; Grañena, A // Bone Marrow Transplantation;12/15/99, Vol. 24 Issue 12, p1285 

    Between April 1996 and May 1998, 20 consecutive patients with Ph chromosome-positive CML in first chronic phase without an HLA-identical sibling received the mini-ICE regimen shortly after diagnosis to mobilize progenitor cells into the peripheral blood (PBPCs). The sex distribution was 12 males...

  • Chronic lymphocytic leukaemia in pregnancy: a case report and literature review. Maxwell, Cynthia; Grady, Rosheen; Crump, Michael // Obstetric Medicine (1753-495X);Dec2009, Vol. 2 Issue 4, p168 

    Chronic lymphocytic leukaemia is a rare condition reported in pregnancy. We review a case of a woman presenting for pregnancy care with active disease and review the literature on this condition. This case raises several important issues with regard to managing complex medical diseases such as...

  • Long-term results of NOPHO ALL-92 and ALL-2000 studies of childhood acute lymphoblastic leukemia. Schmiegelow, K; Forestier, E; Hellebostad, M; Heyman, M; Kristinsson, J; Söderhäll, S; Taskinen, M // Leukemia (08876924);Mar2010, Vol. 24 Issue 3, p670 

    A correction to the article "Long-Term Results of NOPHO ALL-92 and ALL-2000 Studies of Childhood Acute Lymphoblastic Leukemia" that was published in the previous issue is presented.

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics