Secondary polycythemia as a paraneoplastic syndrome of testicular seminoma

Kaito, K.; Otsubo, H.; Usui, N.; Kobayashi, M.
January 2004
Annals of Hematology;Jan2004, Vol. 83 Issue 1, p55
Academic Journal
A 45-year-old man was referred to our hospital because of polycythemia. A physical examination revealed a large tumor in his scrotum enlarged to the size of 13×10 cm. A laboratory examination revealed severe erythrocytosis with a red blood cell count of 6,820×109/L, a hemoglobin concentration of 21.2 g/dL, and a hematocrit of 59.8%. The total red cell volume was increased. A right radical orchidectomy was done with minimum bleeding, and he was diagnosed as having pure seminoma. After the operation, polycythemia improved spontaneously. Polycythemia is a rare complication of seminoma and only two cases have been reported previously. The precise mechanism of polycythemia in our patient could not be clearly evaluated, but clinical course did indicate a close relationship between two distinct disorders.


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