High-resolution second-harmonic optical coherence tomography of collagen in rat-tail tendon

Yi Jiang; Tomov, Ivan V.; Yimin Wang; Zhongping Chen
March 2005
Applied Physics Letters;3/28/2005, Vol. 86 Issue 13, p133901
Academic Journal
A high-resolution second-harmonic optical coherence tomography (SH-OCT) system is demonstrated using a spectrum broadened femtosecond Ti:sapphire laser. An axial resolution of 4.2 μm at the second-harmonic wave center wavelength of 400 nm has been achieved. Because the SH-OCT system uses the second-harmonic generation signals that strongly depend on the orientation, polarization, and local symmetry properties of chiral molecules, this technique provides unique contrast enhancement to conventional optical coherence tomography. The system is applied to image biological tissues of the rat-tail tendon. Highly organized collagen fibrils in the rat-tail tendon can be visualized in recorded images.


Related Articles

  • Dynamically focused optical coherence tomography for endoscopic applications. Divetia, Asheesh; Hsieh, Tsung-Hsi; Zhang, Jun; Chen, Zhongping; Bachman, Mark; Li, Guann-Pyng // Applied Physics Letters;3/7/2005, Vol. 86 Issue 10, p103902 

    We report a demonstration of a small liquid-filled polymer lens that may be used to dynamically provide scanning depth focus for endoscopic optical coherence tomography (OCT) applications. The focal depth of the lens is controlled by changing the hydraulic pressure within the lens, enabling...

  • Optical coherence tomography of cutaneous lupus erythematosus correlates with histopathology. Gambichler, T.; Hyun, J.; Moussa, G.; Tomi, N. S.; Boms, S.; Altmeyer, P.; Hoffmann, K.; Kreuter, A. // Lupus;2007, Vol. 16 Issue 1, p35 

    Diagnosis of cutaneous forms of lupus erythematosus (LE), including chronic discoid LE (CDLE) and subacute cutaneous LE (SCLE), is usually based on characteristic clinical and histopathological findings. We aimed to visualize morphological changes in lesions of cutaneous LE using optical...

  • Integrated and dispersed photon echo studies of nitrile stretching vibration of 4-cyanophenol in methanol. Jeong-Hyon Ha; Kyung-Koo Lee; Kwang-Hee Park; Jun-Ho Choi; Seung-Joon Jeon; Minhaeng Cho // Journal of Chemical Physics;5/28/2009, Vol. 130 Issue 20, p204509 

    By means of integrated and dispersed IR photon echo measurement methods, the vibrational dynamics of C–N stretch modes in 4-cyanophenol and 4-cyanophenoxide in methanol is investigated. The vibrational frequency-frequency correlation function (FFCF) is retrieved from the integrated photon...

  • Depolarization of radiation upon coherent excitation with allowance made for the ground state splitting. Petrashen', A. // Optics & Spectroscopy;Jun2012, Vol. 112 Issue 6, p817 

    It is shown that, if a certain coherence is induced between the low-lying levels of a three-level system, the signal of longitudinal alignment can vanish due to a change in the laser frequency detuning.

  • Photon echo under excitation of a medium by pulses consisting of an arbitrary number of oscillations. Znamenskii, N. N.; Sazonov, S. V. // Optics & Spectroscopy;Mar2008, Vol. 104 Issue 3, p378 

    Echo responses of a three-level medium formed by the λ-scheme of quantum transitions under exposure to optical pulses consisting of an arbitrary number of oscillations have been studied theoretically. The cases of pulses consisting of few optical oscillations (for which the concept of an...

  • Technique of Quantum Memory on the Basis of a Photon Echo in Gases. Moiseev, S.A.; Noskov, M.I. // Optics & Spectroscopy;May2004, Vol. 96 Issue 5, p714 

    The technique of quantum memory based on the use of a photon echo in gases is studied theoretically taking into account three-dimensional specific features in the propagation of light fields and the motion of atoms in a gas. Analytical solutions describing the effects of atomic motion and...

  • Low-Coherence interference microscopy of the internal structure of crystallized blood plasma. Lychagov, V. V.; Kal'yanov, A. L.; Ryabukho, V. P. // Optics & Spectroscopy;Dec2009, Vol. 107 Issue 6, p859 

    The possibility of using full-field low-coherence (white light) interferometry to investigate the surface profile and the internal spatial structure of crystallized drops of blood plasma and to study plasma structuring in real time is discussed. The experimental microtomograms of the central and...

  • Magnetic coherence gratings in a high-flux atomic beam. Tonyushkin, A.; Kumarakrishnan, A.; Turlapov, A.; Sleator, T. // European Physical Journal D -- Atoms, Molecules, Clusters & Opti;Jun2010, Vol. 58 Issue 1, p39 

    Magnetic coherence gratings have been created in a thermal beam of rubidium atoms. The coherence gratings involve superposition of magnetic sublevels of a single hyperfine ground state. These gratings are created via interaction with a single pulse that drives a two-photon transition between...

  • Two-dimensional heterodyned and stimulated infrared photon echoes of N-methylacetamide-D. Zanni, Martin T.; Asplund, Matthew C.; Hochstrasser, Robin M. // Journal of Chemical Physics;3/8/2001, Vol. 114 Issue 10 

    The stimulated infrared photon echo of N-methylacetamide-D [NMAD; CH[sub 3](CO)ND(CH[sub 3])] was measured and used to determine the vibrational frequency correlation function. The correlation function was modeled as a single exponential plus a constant, and it was found that most of the NMAD...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics