TITLE

Effect of vasopressin on sublingual microcirculation in a patient with distributive shock

AUTHOR(S)
Dubois, Marc J.; De Backer, Daniel; Creteur, Jacques; Anane, Sami; Vincent, Jean-Louis
PUB. DATE
June 2003
SOURCE
Intensive Care Medicine;Jun2003, Vol. 29 Issue 6, p1020
SOURCE TYPE
Academic Journal
DOC. TYPE
journal article
ABSTRACT
Objective: To assess the sublingual microcirculation in a patient during vasopressin administration for a distributive shock after cardiopulmonary bypass.Design and Setting: Case-report in the Department of Intensive Care of a university hospital.Patient: A 53 year-old man developed severe distributive shock after cardiac transplant, requiring massive doses of vasopressor agents.Methods: Vasopressin administered twice at a dose of 0.02 U/min increased mean blood pressure and allowed partial weaning of other vasopressor drugs. Microcirculatory alterations were assessed by orthogonal polarization spectral technique: 50% and 60% of capillaries were perfused at baseline, and these proportions did not worsen when vasopressin was administered.Conclusions: Despite its strong vasopressor effects vasopressin infusion did not worsen microcirculatory alterations in this patient with distributive shock following cardiac surgery.
ACCESSION #
16629440

 

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