Does immunonutrition in patients with sepsis do more harm than good?

Heyland, Daren K.; Samis, Andrew
May 2003
Intensive Care Medicine;May2003, Vol. 29 Issue 5, p669
Academic Journal
The article discusses on the issue that whether immunonutrition in patients with sepsis do more harm than good. Almost 2 years ago, we published a meta-analysis of immunonutrition that demonstrated that the overall treatment effect associated with these diets in critically ill patients was a risk ratio (RR) of 1.18. While there was a clear and convincing signal that immunonutrition was beneficial to patients undergoing elective surgery, there was a suggestion that some sub-populations of critically ill patients were being harmed by the intervention, whereas others experienced a beneficial or neutral effect.


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