COMMENTARY: Hemoglobin A1c levels were associated with increased cardiovascular disease and all-cause mortality in persons with and without diabetes

Sigal, Ronald J.
March 2005
ACP Journal Club;Mar/Apr2005, Vol. 142 Issue 2, p52
Academic Journal
The article presents information relating to diabetes mellitus. It is a major risk factor for cardiovascular disease (CVD), and unlike hypertension, smoking, and dyslipidemia, it is becoming more common over time. There is considerable epidemiologic evidence that the risk for CVD begins to increase at lower glycemic levels than would be considered abnormal levels that would not be associated with increased microvascular disease risk. The cutpoint for a normal Hemoglobin A level should be revised downward, as has been done for cholesterol and blood pressure.


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