COMMENTARY: Review: Estrogen improves symptoms of overactive bladder in postmenopausal women

Thacker, Holly L.
March 2005
ACP Journal Club;Mar/Apr2005, Vol. 142 Issue 2, p48
Academic Journal
The article comments on a study which reviews the effects of estrogens for symptoms suggestive of overactive bladder. The Women's Health Initiative findings indicated that systemic hormone replacement therapy should be limited in older, asymptomatic postmenopausal women because of adverse effects. Stopping systemic hormone therapy will result in an increase in the incidence of genital atrophy. Estrogen therapy restores the integrity of the genitourinary tissue, particularly the highly estrogen-rich tissue of the trigone of the bladder, urethra, and lower one third of the vagina.


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