TITLE

COMMENTARY: Lumiracoxib reduced ulcer complications compared with ibuprofen and naproxen in osteoarthritis and did not increase cardiovascular outcomes

AUTHOR(S)
Hart, Lawrence
PUB. DATE
March 2005
SOURCE
ACP Journal Club;Mar/Apr2005, Vol. 142 Issue 2, p47
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article comments on a study which presents a comparison of lumiracoxib with naproxen and ibuprofen in the Therapeutic Arthritis Research and Gastrointestinal Event Trial (TARGET). The major conclusions reported by TARGET were that lumiracoxib showed a 3 to 4 fold reduction in ulcer complications compared with naproxen and ibuprofen, and the positive gastrointestinal outcome was not associated with an increased rate of serious cardiovascular events. The data showed no difference in the incidence of myocardial infarction between lumiracoxib and either ibuprofen or naproxen, regardless of aspirin use.
ACCESSION #
16486594

 

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