COMMENTARY: Etidronate, calcium, or both did not reduce fracture rates in patients with asthma receiving glucocorticoid treatment

Jamal, Sophie A.
March 2005
ACP Journal Club;Mar/Apr2005, Vol. 142 Issue 2, p44
Academic Journal
The article comments on a study which examines the effects of etidronate, calcium, or placebo on bone mineral density (BMD) and fractures in patients taking oral or inhaled glucocorticoids or both for asthma. Patients randomized to etidronate had a 5% increase in lumbar spine BMD. No difference between groups existed in hip BMD or fractures. Findings from this study showing that etidronate decreases hip and nonspinal fractures in patients treated with steroids and in postmenopausal women suggest that etidronate is not the best choice.


Related Articles

  • Etidronate, calcium, or both did not reduce fracture rates in patients with asthma receiving glucocorticoid treatment.  // ACP Journal Club;Mar/Apr2005, Vol. 142 Issue 2, p44 

    The article cites a study which states that etidronate, calcium, or both did not reduce fracture rates in patients with asthma receiving glucocorticoid treatment. The study was published in the 2004 issue of the journal "Thorax." The study included 352 men and women 50 to 70 years of age who...

  • Do allergy shots help seasonal allergies more than antihistamines and nasal steroids? Fagnan, L. J.; Smits, Ariel K.; Judkins, Dolores Zegar // Journal of Family Practice;Oct2006, Vol. 55 Issue 10, p898 

    The article discusses the effectiveness of allergen immunotherapy and antihistamines in the treatment of seasonal allergic rhinitis with or without nasal steroids. Immunotherapy is not recommended for most patients with seasonal allergic rhinitis. For patients that require medication, studies...

  • Etidronate Tx effective for postmenopausal osteoporosis.  // Geriatrics;Sep1990, Vol. 45 Issue 9, p28 

    The article discusses the effectiveness of the compound etidronate for menopausal osteoporosis. Intermittent cyclical therapy with etidronate disodium for 2 years increases spinal bone mass and reduces the incidence of new vertebral fractures in women with postmenopausal osteoporosis, according...

  • Budesonide Turbuhaler Delivered Once Daily Improves Health-Related Quality of Life in Adult Patients with Non--Steroid-Dependent Asthma. Banov, Charles; Howland III, William C.; Lumry, William R.; Parasuraman, Bhash; Uryniak, Thomas; Liljas, Bengt // Allergy & Asthma Proceedings;Mar/Apr2003, Vol. 24 Issue 2, p129 

    Budesonide inhalation powder via the dry-powder multidose inhaler Turhuhaler (budesonide Turhuhaler) has been shown to improve lung function and symptoms in adults with asthma. In this double-blind, placebo-controlled, multicenter trial, we evaluated the effects of once-daily hudesonide...

  • Review: 700 to 800 IU/d of vitamin D reduces hip and nonvertebral fractures in older persons.  // ACP Journal Club;Nov/Dec2005, Vol. 143 Issue 3, p72 

    This article presents information on a clinical study according to which 700 to 800 IU/d of vitamin D reduces hip and nonvertebral fractures in older persons. The study explored whether oral vitamin D supplementation prevents hip and any nonvertebral fractures in older persons. Blinded...

  • Randomized Trial of the Effects of Risedronate on Vertebral Fractures in Women with Established Postmenopausal Osteoporosis. Reginster, J.-Y.; Minne, H. W.; Sorensen, O. H.; Hooper, M.; Roux, C.; Brandi, M. L.; Lund, B.; Ethgen, D.; Pack, S.; Roumagnac, I.; Eastell, R. // Osteoporosis International;Jan2000, Vol. 11 Issue 1, p83 

    : The purpose of this randomized, double-masked, placebo-controlled study was to determine the efficacy and safety of risedronate in the prevention of vertebral fractures in postmenopausal women with established osteoporosis. The study was conducted at 80 study centers in Europe and Australia....

  • Combined Calcium and Vitamin D3 Supplementation in Elderly Women: Confirmation of Reversal of Secondary Hyperparathyroidism and Hip Fracture Risk: The Decalyos II Study. Chapuy, M. C.; Pamphile, R.; Paris, E.; Kempf, C.; Schlichting, M.; Arnaud, S.; Garnero, P.; Meunier, P. J. // Osteoporosis International;Mar2002, Vol. 13 Issue 3, p257 

    : Vitamin D insufficiency and low calcium intake contribute to increase parathyroid function and bone fragility in elderly people. Calcium and vitamin D supplements can reverse secondary hyperparathyroidism thus preventing hip fractures, as proved by Decalyos I. Decalyos II is a 2-year,...

  • Uso de dosis única de betametasona en el hemorroidectomía convencional. García-Nuñez, Lius Manuel; Belmonte-Montes, Carlos; Guerrero-Guerrero, Víctor Hugo // Revista de Sanidad Militar;may/jun2007, Vol. 61 Issue 3, p152 

    Introduction. Anorectal pain is the most common symptom in patients undergoing conventional hemmorrhoidectomy. Management with NSAID is not effective as a analgesic therapy. Steroids are very effective inhibitors of inflammatory process and anorectal pain mediators. We consider that a...

  • Antivirals and Bell's Palsy?  // OB/GYN Clinical Alert;Dec2007, Vol. 24 Issue 8, p2 

    The article reports on the results of a study regarding the usefulness of steroids and antivirals in treating Bell's palsy. A number of patients with new onset of the disease were randomized to 10 days of treatment with prednisolone, acyclovir, both agents or placebo. It has been concluded that...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics