TITLE

Review: β-blockers reduce mortality and therapy withdrawal in heart failure but increase dizziness and bradycardia

PUB. DATE
March 2005
SOURCE
ACP Journal Club;Mar/Apr2005, Vol. 142 Issue 2, p36
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article cites a survey of studies related to risks associated with β-blocker therapy. Studies were selected if they were randomized controlled trials (RCTs) that used noncrossover designs and compared β-blocker therapy with placebo in patients with HF with left ventricular systolic dysfunction. In patients with heart failure (HF) and systolic dysfunction, β-blocker therapy reduces the risks for all-cause mortality, HF hospitalization, worsening HF, and all-cause withdrawal of therapy, but is associated with increased risks for dizziness and bradycardia. The study was published in the 2004 issue of the journal "Arch International Medicine."
ACCESSION #
16486573

 

Related Articles

  • COMMENTARY: Review: β-blockers reduce mortality and therapy withdrawal in heart failure but increase dizziness and bradycardia. O'Malley, Patrick G. // ACP Journal Club;Mar/Apr2005, Vol. 142 Issue 2, p36 

    The article reports that β-blockers reduce mortality and therapy withdrawal in heart failure but increase dizziness and bradycardia. Other side effects attributable to β-blockers include depression and sexual dysfunction. In patients with heart failure and systolic dysfunction, one should...

  • Review: β blockers reduce mortality and therapy withdrawal in heart failure but increase dizziness and bradycardia. O'Malley, Patrick G. // Evidence Based Medicine;Apr2005, Vol. 10 Issue 2, p42 

    The article cites a research study, which reveals that beta blockers reduce mortality and therapy withdrawal in heart failure (HF) but increase dizziness and bradycardia. The researchers concluded that in patients with HF with systolic dysfunction, beta blockers reduce the risks of all cause...

  • β‐blockers in left ventricular systolic dysfunction—from evidence to practice. BANDYOPADHYAY, SYAMASIS; O'MAHONY, M. SINEAD // Age & Ageing;Jan2002, Vol. 31 Issue 1, p23 

    Five percent of all hospital medical admissions are patients with heart failure. The incidence is about one new case per 1000 of the general population per year, increasing to >10 per 1000 in those aged 85 years. Although the evidence that β‐blockers reduce mortality by about 36%...

  • How do Beta-Blockers Protect After Myocardial Infarction? Bigger Jr., J. Thomas; Coromilas, James // Annals of Internal Medicine;Aug84, Vol. 101 Issue 2, p256 

    Explores the mechanism of the beneficial effects of beta-adrenergic blocking drugs after myocardial infarction. Factor that might exert some of its beneficial effect on survivorship through its postinfarction antiarrhythmic effects; Effect on sympathetic nerves that increases the heterogeneity...

  • Effect of Carvedilol in Patients with Congestive Heart Failure. Sexton, Sumi M. // American Family Physician;2/1/2003, Vol. 67 Issue 3, p588 

    Discusses studies on the effect of carvedilol on patients with severe chronic heart disease, conducted by M. Packer et al. 'Effect of Carvedilol on the Morbidity of Patients With Severe Chronic Heart Failure: Results of the Carvedilol Prospective Randomized Cumulative Survival (COPERNICUS)...

  • Clinical Relevance of Intrinsic Sympathomimetic Activity of Beta Blockers Used in Angina. Kostis, J. B.; DeFelice, E. A.; Frishman, W.; Hosier, M.; Krieger, S. K.; Aglitz, N.; Kuo, P. T. // Angiology;Nov1981, Vol. 32 Issue 11, p780 

    β-blockers are effective in the symptomatic relief of angina pectoris by decreasing myocardial oxygen demand during effort and emotional stress. Agents with ISA such as pindolol produce effective β-blockade during effort or emotional stress while conferring significant protection from...

  • Beta-blockers and hypertension. Elliott, William T. // Neurology Alert;Dec2008 Pharmacology, p2 

    The article discusses a research on the role of beta-blocker-associated bradycardia in increased risk of cardiovascular events. It references a study by S. Bangalore et al published in a 2008 issue of the "Journal of American College of Cardiology." The study is a meta-analysis of nine...

  • Review: Evidence of benefit for perioperative β-blockers in noncardiac surgery is unreliable.  // ACP Journal Club;Jan/Feb2006, Vol. 144 Issue 1, p17 

    This article focuses on the efficacy of perioperative β-blockers in noncardiac surgery. Studies were selected if they were randomized controlled trials (RCTs) that assessed β-blockers in patients having noncardiac surgery. RCTs were excluded if there was no control group that received...

  • Beta-blockade and other perioperative pharmacological protectors: what is now available and efficacious? Sear, J. W.; Higham, H.; Foex, P. // BJA: The British Journal of Anaesthesia;Sep2015, Vol. 115 Issue 3, p333 

    No abstract available.

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics